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Serving leading biopharmaceutical companies globally:

Johnson and Johnson

Generated: October 23, 2017

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Details for Patent: 3,950,529

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Summary for Patent: 3,950,529

Title: Amino acid formulations for patients with liver disease and method of using same
Abstract:Amino acid formulations for administration to human patients with liver disease comprise mixtures of essential amino acids combined in novel relative proportions, and preferably also include non-essential amino acids. In particular, the combined molar proportions of isoleucine, leucine, and valine are from 40 to 300 times the molar proportion of tryptophan and from 15 to 135 times the molar proportion of phenylalanine, or phenylalanine and tyrosine. The formulations may be adapted for either intravenous or oral administration, but the preferred method of administration is by hyperalimentation infusion. The formulations and method can be utilized to provide nutritional support for liver diseased patients while reducing the incidence and severity of hepatic encephalopathy, and/or as primary therapy for treatment of hepatic encephalopathy.
Inventor(s): Fischer; Josef E. (Boston, MA), Yoshimura; Norman N. (Woodland Hills, CA), Westman; Thomas L. (Northridge, CA), Deindoerfer; Fred H. (Northridge, CA)
Assignee: Massachusetts General Hospital (Boston, MA) American Hospital Supply Corporation (Evanston, IL)
Application Number:05/546,689
Patent Claim Types:
see list of patent claims
Formulation; Compound; Dosage form; Use;

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International Patent Family for Patent: 3,950,529

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia1024076► Subscribe
Belgium838231► Subscribe
Canada1050890► Subscribe
Germany2556100► Subscribe
Denmark579875► Subscribe
France2299023► Subscribe
United Kingdom1507951► Subscribe
Israel48621► Subscribe
India143663► Subscribe
Italy1067502► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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