Details for Patent: 3,931,195
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Summary for Patent: 3,931,195
Title: | Substituted piperidines |
Abstract: | The compounds are of the heterocyclic class of 2-phenethylpiperidines having an amido substituent in the ortho position of the phenethyl moiety. Substituents in the ortho position include formamido, benzamido, cinnamamido, 2-thiophenecarboxamido, alkanesulfonamido and alkanoylamido. They are useful as antiarrhythmic and/or antiserotonin agents. The novel compounds are prepared by reaction of appropriately substituted o-aminophenethylpiperidines and the carbonyl or sulfonyl halides or anhydrides. Typical embodiments of this invention are 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide and 2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide. |
Inventor(s): | Dykstra; Stanley J. (Evansville, IN), Minielli; Joseph L. (Evansville, IN) |
Assignee: | Mead Johnson & Company (Evansville, IN) |
Application Number: | 05/384,341 |
Patent Claim Types: see list of patent claims | Compound; |
Drugs Protected by US Patent 3,931,195
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International Family Members for US Patent 3,931,195
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