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Generated: July 27, 2017

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Title: Alpha-aryl-4-substituted piperidinoalkanol derivatives
Abstract:Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1## Wherein R represents hydrogen or hydroxy; R.sup.1 represents hydrogen; or R and R.sup.1 taken together form a second bond between the carbon atoms bearing R and R.sup.1 ; n is a positive whole integer of from 1 to 3; Z represents thienyl, phenyl, or substituted phenyl wherein the substituents on the substituted phenyl may be attached at the ortho, meta, or para positions of the phenyl ring and are selected from halogen, a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a lower alkoxy group of from 1 to 4 carbon atoms, di(lower alkylamino, or a saturated monocyclic heterocyclic group such as pyrrolidino, piperidino, morpholino, or N-(lower)alkylpiperazino. Pharmaceutically acceptable acid addition salts and individual optical isomers of compounds of the above formula are also included within this invention.
Inventor(s): Carr; Albert A. (Cincinnati, OH), Kinsolving; Richard (Cincinnati, OH)
Assignee: Richardson-Merrell Inc. (New York, NY)
Application Number:05/378,561
Patent Claim Types:
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Compound;

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International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina195314► Subscribe
Austria321917► Subscribe
Austria323742► Subscribe
Australia467361► Subscribe
Australia4989372► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving 500+ biopharmaceutical companies globally:

Deloitte
Boehringer Ingelheim
Johnson and Johnson
Teva
Fuji
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US Army
Queensland Health
Harvard Business School

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