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Last Updated: April 24, 2024

Details for Patent: 3,864,487

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Summary for Patent: 3,864,487

Title:	Antiarhythmic pharmaceutical preparation containing ethyl 10-.alpha.-morpholylpropionyl) phenthiazine-2-carbamate hydrochloride
Abstract:	A method for preparing a novel composition of matter, ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate hydrochloride, having the formula ##SPC1## Which comprises reacting ethyl phenthiazine-2-carbamate with .beta.-chloropropionyl chloride in an inert organic solvent at the boiling point of the solvent used, condensing the resulting ethyl 10-(.beta.-chloropropionyl)-phenthiazine-2-carbamate with morpholine in an inert organic solvent, treating the ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate with hydrogen chloride, and separating the desired compound. The novel compound, ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate hydrochloride, is the active principle of an antiarhythmic pharmaceutical preparation.
Inventor(s):	Gritsenko; Anna Nikitichna (Moscow, SU), Vikhlyaev; Jury Ivanovich (Moscow, SU), Zhuravlev; Semen Vladimirovich (Moscow, SU), Kaverina; Natalya Veniaminovna (Moscow, SU), Senova; Zlata Petrovna (Moscow, SU), Ulyanova; Olga Vasilievna (Moscow, SU)
Assignee:
Application Number:	05/172,216
Patent Claim Types: see list of patent claims	Composition; Compound; Dosage form; Formulation;

Drugs Protected by US Patent 3,864,487

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 3,864,487

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Germany	2014201	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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