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Serving leading biopharmaceutical companies globally:

Harvard Business School
Daiichi Sankyo
Johnson and Johnson
US Army

Generated: December 15, 2017

DrugPatentWatch Database Preview

Details for Patent: 3,864,487

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Summary for Patent: 3,864,487

Title: Antiarhythmic pharmaceutical preparation containing ethyl 10-.alpha.-morpholylpropionyl) phenthiazine-2-carbamate hydrochloride
Abstract:A method for preparing a novel composition of matter, ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate hydrochloride, having the formula ##SPC1## Which comprises reacting ethyl phenthiazine-2-carbamate with .beta.-chloropropionyl chloride in an inert organic solvent at the boiling point of the solvent used, condensing the resulting ethyl 10-(.beta.-chloropropionyl)-phenthiazine-2-carbamate with morpholine in an inert organic solvent, treating the ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate with hydrogen chloride, and separating the desired compound. The novel compound, ethyl 10-(.beta.-morpholylpropionyl)-phenthiazine-2-carbamate hydrochloride, is the active principle of an antiarhythmic pharmaceutical preparation.
Inventor(s): Gritsenko; Anna Nikitichna (Moscow, SU), Vikhlyaev; Jury Ivanovich (Moscow, SU), Zhuravlev; Semen Vladimirovich (Moscow, SU), Kaverina; Natalya Veniaminovna (Moscow, SU), Senova; Zlata Petrovna (Moscow, SU), Ulyanova; Olga Vasilievna (Moscow, SU)
Application Number:05/172,216
Patent Claim Types:
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Composition; Compound; Dosage form; Formulation;

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International Patent Family for Patent: 3,864,487

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany2014201► Subscribe
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Serving leading biopharmaceutical companies globally:

Farmers Insurance
US Department of Justice
Fish and Richardson
Argus Health
US Army

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