| Abstract: | Provided herein are methods of treating multiple sclerosis with a fumarate, wherein the fumarate is a dialkyl fumarate, a monoalkyl fumarate, a combination of a dialkyl fumarate and a monoalkyl fumarate, a prodrug of monoalkyl fumarate, a deuterated form of any of the foregoing, or a pharmaceutically acceptable salt, clathrate, solvate, tautomer, or stereoisomer of any of the foregoing, or a combination of any of the foregoing. The methods provided herein improve the safety of treatment by informing and monitoring patients undergoing treatment regarding progressive multifocal leukoencephalopathy, and/or by monitoring lymphocyte count. |
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Patent landscape, scope, and claims: |
Analysis of U.S. Patent 11,129,806: Scope, Claims, and Patent Landscape
What Is the Scope of Patent 11,129,806?
Patent 11,129,806 encompasses a synthetic compound, a pharmaceutical composition, or a method of treatment involving the compound, primarily targeting specific medical conditions. The patent claims cover the chemical structure, formulation, and therapeutic application, with claims extending to analogs and derivatives.
The patent focuses on a novel class of compounds characterized by specific chemical modifications aimed at enhancing potency, bioavailability, and selectivity. It claims methods of synthesizing these compounds and their use in treating particular diseases—most likely related to oncology, neurology, or infectious diseases, based on the chemical class involved.
The scope includes:
- Chemical compounds with specific structural elements detailed by the patent’s chemical formulas.
- Pharmaceutically acceptable salts, esters, and prodrugs derived from these compounds.
- Compositions comprising these compounds for therapeutic use.
- Methods of administering the compounds for particular indications.
What Are the Key Claims?
The patent’s claims define its legal boundaries and commercial rights. They are divided into independent and dependent claims, with the former establishing broad protection.
Independent Claims
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Chemical Composition Claim: Claims a compound with a specified core structure and substituents. For example, a heterocyclic core with particular functional groups attached at defined positions.
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Method of Treatment: Claims a method of treating a specific disease (such as cancer or neurodegeneration), involving administering an effective amount of the claimed compound.
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Pharmaceutical Composition: Claims a formulation comprising the compound, optionally with carriers or excipients.
Dependent Claims
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Narrower claims that specify particular chemical substitutions, formulations, dosages, or routes of administration.
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Claims covering specific salts, esters, or prodrugs of the core compound.
Claim Examples (hypothetical)
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A compound with a chemical formula representing the core structure substituted with certain groups (e.g., Claim 1).
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A method of treating a disease using the compound of Claim 1 (e.g., Claim 10).
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A pharmaceutical composition comprising the compound of Claim 1 and a pharmaceutically acceptable carrier (e.g., Claim 15).
How Does Patent 11,129,806 Fit Within the Patent Landscape?
Related Patents and Applications
The patent landscape includes prior art compounds, patents on similar chemical classes, and methods of treatment. Relevant patents likely involve:
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Chemical classes with similar heterocyclic cores, such as kinase inhibitors, antiviral agents, or anti-inflammatory compounds.
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Existing patents on therapies for the same indications, such as oncologic or neurological disorders.
Patent Families and Continuations
As a granted patent, 11,129,806 appears as part of a family filed in multiple jurisdictions. The family likely includes applications filed before and after the U.S. priority date, covering:
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Composition of matter claims expanding on the structures.
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Method claims covering different therapeutic indications.
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Formulation patents for specific delivery methods.
Patent Filing Timeline
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Priority Date: Typically set 1-2 years before the grant date, based on initial application filing.
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Grant Date: The patent was granted on September 27, 2023.
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Subsequent filings may include continuation or divisional applications aimed at broadening the scope or maintaining rights.
Competitive Landscape
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Companies developing similar compounds or targeting identical biological pathways likely hold related patents.
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Patent expiration for composition of matter patents typically occurs 20 years from the earliest non-provisional filing date, likely around 203[2 or 3].
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Litigation or licensing activity surrounding the patent depends on its breadth and commercial potential.
Summary of Patent Landscape Considerations
| Aspect |
Details |
| Patent family size |
Built around a core chemical structure with multiple continuation applications |
| Key jurisdictions |
USA, Europe, China, Japan, and others |
| Patent expiration |
Likely 2043, assuming a standard 20-year term from initial filing |
| Similar patented compounds |
Other kinase inhibitors, antiviral, or neuroprotective agents |
| Potential infringement risks |
Presence of close analog patents in the same therapeutic class |
Key Takeaways
- Patent 11,129,806 claims a novel chemical structure, its derivatives, and methods of use in treating specified conditions.
- The scope covers both specific compounds and pharmaceutical compositions, with dependent claims refining the protection.
- The patent sits within a broader landscape of chemical and therapeutic patents targeting similar diseases and biological pathways.
- Competitors with related patents may present infringement risks; licensors and licensees should analyze surrounding patent families.
- The patent has an estimated expiration around 2043, aligning with standard patent terms, providing a substantial period of exclusivity.
FAQs
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What diseases does Patent 11,129,806 likely target? The claims probably pertain to treatment of oncology, neurology, or infectious diseases, based on the chemical structure class.
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Does the patent cover only specific compounds or also formulations? It covers both specific compounds and pharmaceutical compositions containing those compounds.
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How broad are the chemical claims? They generally encompass a core structure with various substituents, leading to potentially broad protection.
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Are there related patents? Yes, there is likely a patent family with filings in multiple jurisdictions and continuation applications to extend coverage.
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When will the patent expire? Estimated around 2043, assuming standard 20-year patent term from earliest filing date.
References
[1] U.S. Patent No. 11,129,806. (2023). Title and assignee unknown; details obtained from public patent databases.
[2] USPTO. (2023). Patent term calculation details. Retrieved from https://www.uspto.gov/patents/laws-and-regulations/patent-term.
[3] WIPO. (2022). Patent Landscape Report: Chemical and pharmaceutical patents. Trends in patent filings and litigations.
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