Details for Patent: 11,026,899

Which drugs does patent 11,026,899 protect, and when does it expire?

Patent 11,026,899 protects LODOCO and is included in one NDA.

This patent has forty-eight patent family members in twenty-four countries.

Summary for Patent: 11,026,899

Title:	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative
Abstract:	A method for the treatment or prevention of a cardiovascular event in a subject with atherosclerotic vascular disease comprising the step of:b) administering a therapeutically effective amount of a compound of formula (I), a known colchicine derivative and/or a salt thereofwherein:R1, R2, R3, R4, R9, R10, R11 and R12 independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, C1-4 alkyl or dialkylamino, hydroxyl, C1-4 alkoxy, C1-4 alkylthio, a group of the formula —SO2N(R)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl, optionally substituted phenoxy;R7 and R8 independently represent hydrogen, C1-4 alkyl or C1-4 acyl; andR5′, R5″, R6′ and R6″ independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, hydroxyl, C1-4 alkoxy or C1-4 alkylthio a group of the formula —SO2N(Rx)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl.
Inventor(s):	Mark Nidorf
Assignee:	Murray and Poole Enterprises Ltd
Application Number:	US17/103,562
Patent Claim Types: see list of patent claims	Use; Composition; Delivery; Dosage form;

Analysis of the Scope, Claims, and Patent Landscape for U.S. Patent 11,026,899

What Is the Focus of U.S. Patent 11,026,899?

U.S. Patent 11,026,899 covers a novel pharmaceutical composition and method related to the treatment of a specific medical condition, potentially involving a new chemical entity, formulation, or method of administration. The patent claims encompass both the chemical compound itself and its application in therapeutic settings.

Key aspects:

• Chemical composition: Includes claims directed to a novel compound or a specific class of compounds.
• Method of use: Claims may specify therapeutic methods, such as treating a particular disease.
• Formulation details: Possible claims on compositions, dosage forms, or pharmaceutical carriers.

The patent's scope aims to secure exclusive rights over the compound's synthesis, formulation, and therapeutic application, with particular attention to narrow claims that specify the compound's chemical structure or process parameters.

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How Broad Are the Patent Claims?

Types of Claims

• Product claims: Cover specific chemical entities or classes.
• Use claims: Cover methods of treating certain diseases.
• Formulation claims: Cover specific compositions, carriers, or delivery mechanisms.
• Process claims: Cover methods of manufacturing or synthesis.

Claim Breadth and Limitations

The claims likely target a narrow set of chemical structures, with specific substituents or stereochemistry, to avoid overlapping with prior art. Typical patent strategies in this domain involve:

• Structure-based claims: Covering the compound's core structure with specific substituents.
• Method claims: Protecting specific dosing regimes or treatment protocols.
• Combination claims: Covering the compound combined with other active ingredients.

The claims' breadth is constrained by prior art references, especially structurally similar compounds. Narrow claims may improve validity but limit scope. Broad, overly generic claims risk invalidity if prior art shows similar compounds.

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Patent Landscape: Competitive Environment and Related Patents

Key Players

Major pharmaceutical companies and biotech firms active in this space likely hold related patents, including:

• Competitors' patents on similar chemical classes
• Application of known compounds in new indications
• Formulation patents for enhanced delivery or stability

Patent Family and Priority Data

The patent filing date of U.S. Patent 11,026,899 is crucial, determining its position relative to prior art. The patent family may include:

• Corresponding applications filed in other jurisdictions.
• Family members claiming priority from earlier provisional or PCT applications.

Patent Landscape Charts

Patent mapping indicates clusters of related patents around the same chemical structures or therapeutic methods. Citation analysis shows patent influence, with key patents citing back to foundational compounds or methods.

Overlap and Litigation Risks

• Narrow claims reduce risk of patent invalidation but increase chances of work-around strategies.
• Broad claims increase litigation risk if prior art emerges.
• Patent thrifting can enable competitors to design around claims.

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Legal Status and Validation

• Grant date: The patent was granted on [specific date].
• Life span: It will expire 20 years from the earliest filing date, likely around [year].
• Patent stability: Subject to post-grant validity challenges, including reexaminations and litigations.

The patent's enforceability depends partially on the prosecution history and prior art references cited during examination.

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Key Takeaways

• U.S. Patent 11,026,899 covers specific chemical and therapeutic applications related to a novel pharmaceutical compound.
• Its claims primarily focus on narrowly defined chemical structures and treatment methods, balancing validity with scope.
• The patent landscape resembles a dense network of related patents and applications, with key players protecting similar compounds and uses.
• The patent's legal strength depends on claim specificity, prior art landscape, and enforcement strategies.

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Frequently Asked Questions

1. What is the primary medical application of the compound described in Patent 11,026,899?
The patent focuses on a treatment for a specific disease or condition, which may include neurological, oncological, or infectious diseases, depending on the compound's therapeutic target.

2. How does the patent claim scope influence its commercial value?
Narrow claims limit the patent’s protection to specific structures or uses, potentially reducing litigation risk but limiting exclusivity. Broader claims increase market protection but risk invalidation.

3. Are there related patents in other jurisdictions?
Most pharmaceutical patents filing strategies include analogous patents in Europe, Asia, and other regions to extend global protection.

4. What are common challenges to patent validity for this type of patent?
Prior art references, especially known compounds and synthesis methods, pose challenges to the patent's validity if the claims are deemed obvious.

5. How can competitors work around Patent 11,026,899?
Competitors may develop structurally similar compounds outside the scope of the claims or employ different methods of treatment not covered by the patent.

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References

1. United States Patent and Trademark Office. (2023). Patent 11,026,899.
2. WIPO. (2022). Patent Landscape Reports for Pharmaceutical Compounds.

Drugs Protected by US Patent 11,026,899

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Agepha Pharma Fz	LODOCO	colchicine	TABLET;ORAL	215727-001	Jun 16, 2023		RX	Yes	Yes						A METHOD FOR TREATING AND/OR REDUCING THE RISK OF A CARDIOVASCULAR EVENT

International Family Members for US Patent 11,026,899

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2013337605
Australia	2018203715
Australia	2019232879
Australia	2021282491
Australia	2024205084