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Last Updated: May 20, 2025

Details for Patent: 10,945,948


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Which drugs does patent 10,945,948 protect, and when does it expire?

Patent 10,945,948 protects EYSUVIS and is included in one NDA.

This patent has sixty-five patent family members in twelve countries.

Summary for Patent: 10,945,948
Title:Compositions and methods for ophthalmic and/or other applications
Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
Inventor(s): Popov; Alexey (Waltham, MA), Enlow; Elizabeth M. (Waltham, MA), Chen; Hongming (Belmont, MA), Bourassa; James (Somerville, MA)
Assignee: The Johns Hopkins University (Baltimore, MD)
Application Number:16/988,459
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 10,945,948

Introduction

The United States Patent 10,945,948, titled "Compositions and methods for ophthalmic and/or other applications," is a patent that covers innovative particles, compositions, and methods designed to aid in particle transport in mucus. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

The patent, assigned the number US10,945,948B2, was published on March 16, 2021. It pertains to compositions and methods that enhance the transport of particles through mucus, which is particularly relevant for ophthalmic and other medical applications[4].

Scope of the Invention

The scope of the invention is defined by its ability to improve the transport of particles in mucus, a critical aspect for various medical treatments, especially those involving the eyes. Here are some key aspects of the scope:

Particles and Compositions

The patent describes specific particles and compositions that are designed to interact with mucus in a way that facilitates the transport of these particles. These particles can be used in various formulations, including eye drops, to ensure effective delivery of therapeutic agents[4].

Methods of Use

The methods outlined in the patent include the application of these particles and compositions in ophthalmic treatments. The focus is on enhancing the efficacy of treatments by improving the penetration and retention of therapeutic agents in the mucus layer of the eye[4].

Claims Analysis

The claims of a patent are crucial as they define the legal boundaries of the invention. Here’s a detailed look at the types of claims found in this patent:

Independent Claims

Independent claims are those that stand alone and do not depend on other claims. In this patent, independent claims typically describe the core components of the invention, such as the specific particles, their composition, and the methods of using these particles to enhance mucus transport[4].

Dependent Claims

Dependent claims build upon the independent claims and provide additional details or limitations. These claims might specify particular applications, such as the use of the particles in eye drops, or additional steps in the method of treatment[4].

Examples of Claims

To illustrate, here are some examples of what the claims might look like:

  • Claim 1: A composition comprising particles designed to interact with mucus to enhance transport, wherein the particles are formulated for ophthalmic use.
  • Claim 2: The composition of Claim 1, wherein the particles are incorporated into eye drops for treating ocular conditions.
  • Claim 3: A method of treating an ocular condition using the composition of Claim 1, wherein the particles are applied to the eye to enhance the transport of therapeutic agents through the mucus layer.

Patent Eligibility and Subject Matter

The patent eligibility of inventions like this one is governed by the USPTO's subject matter eligibility criteria, which have been refined in recent updates. For instance, the 2024 USPTO guidance update emphasizes the importance of integrating judicial exceptions into practical applications to ensure patent eligibility[1].

Practical Application

To meet the criteria for patent eligibility, the claims must demonstrate a practical application that goes beyond mere abstract ideas or routine data processing. In this case, the claims must show how the particles and compositions provide a tangible benefit, such as improving the efficacy of ophthalmic treatments by enhancing particle transport in mucus[1].

Patent Landscape

The patent landscape for this invention involves several key aspects:

Prior Art

The patent must be novel and non-obvious over the prior art. The prior art in this field includes existing methods and compositions for enhancing particle transport in mucus, and the patent must demonstrate significant improvements or differences from these existing technologies[4].

Competing Patents

Other patents in the field of ophthalmic treatments and mucus transport may pose competition. The uniqueness of the particles and compositions, as well as the specific methods of use, must be clearly differentiated from these competing patents to ensure the validity and enforceability of the patent[4].

Future Innovations

The patent landscape is dynamic, and future innovations in this field could impact the scope and validity of this patent. Continuous monitoring of new developments and adjustments to the claims or methods may be necessary to maintain the patent's relevance and enforceability[3].

Key Takeaways

  • Innovation in Particle Transport: The patent introduces innovative particles and compositions that enhance the transport of therapeutic agents through mucus, particularly in ophthalmic applications.
  • Practical Application: The claims must demonstrate a practical application that integrates judicial exceptions into tangible benefits, ensuring patent eligibility.
  • Competitive Landscape: The patent must be differentiated from prior art and competing patents to maintain its validity and enforceability.
  • Dynamic Patent Landscape: Continuous monitoring of new developments is essential to adapt and maintain the patent's relevance.

FAQs

  1. What is the main focus of United States Patent 10,945,948?

    • The main focus is on compositions and methods that enhance the transport of particles through mucus, particularly for ophthalmic applications.
  2. How do the claims in this patent ensure patent eligibility?

    • The claims must integrate judicial exceptions into practical applications, demonstrating tangible benefits such as improved efficacy in ophthalmic treatments.
  3. What is the significance of prior art in this patent?

    • Prior art is crucial as it sets the baseline against which the novelty and non-obviousness of the invention are evaluated.
  4. How does the patent landscape impact this invention?

    • The patent landscape, including competing patents and future innovations, requires continuous monitoring to ensure the patent remains valid and enforceable.
  5. What are the potential applications of this invention beyond ophthalmic use?

    • While the patent is specifically tailored for ophthalmic use, the principles of enhancing particle transport in mucus could be applied to other medical fields where mucus is a barrier to treatment.

Sources

  1. Understanding the 2024 USPTO Guidance Update on AI Patent - Mintz
  2. U.S. Patent and Trademark Office (USPTO) | USAGov
  3. Patent Claims and Patent Scope - SSRN
  4. US10945948B2 - Compositions and methods for ophthalmic and/or other applications - Google Patents

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Drugs Protected by US Patent 10,945,948

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alcon Labs Inc EYSUVIS loteprednol etabonate SUSPENSION/DROPS;OPHTHALMIC 210933-001 Oct 26, 2020 RX Yes Yes ⤷  Try for Free ⤷  Try for Free A METHOD FOR TREATING DRY EYE IN A PATIENT ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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