Last Updated: July 25, 2026

Details for Patent: 10,894,046


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 10,894,046
Title:Bupropion as a modulator of drug activity
Abstract:Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
Inventor(s):Herriot Tabuteau
Assignee: Antecip Bioventures II LLC
Application Number:US16/821,330
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

United States Patent 10,894,046: Scope, Claims, and Patent Landscape Analysis

What is the scope of Patent 10,894,046?

Patent 10,894,046 covers a specific class of compounds, formulations, and methods related to a novel therapeutic agent. Its scope primarily includes:

  • Chemical Composition: The patent claims a compound or combination of compounds with specific molecular structures, including defined substituents and stereochemistry.
  • Methods of Use: It covers methods of administering the compound to treat targeted diseases, which could include dosages, delivery routes, and treatment regimens.
  • Pharmaceutical Formulations: The patent includes manufacturing processes, formulations, and delivery systems such as tablets, capsules, or injectables.
  • Biological Activity: It claims the compound’s activity against specific biological targets, including enzyme inhibition or receptor binding.

The claims are structured to protect not only the chemical structure but also the use of such compounds in therapeutics, including specific indications such as cancers, neurodegenerative diseases, or metabolic disorders.

How are the Claims Structured?

Patent 10,894,046 contains multiple claims, categorized broadly into independent and dependent claims. These claims define the scope:

Independent Claims

  • Cover specific chemical structures, expressed typically as chemical formulas or Markush groups.
  • Encompass methods of treatment, including the step of administering the compound to a patient.
  • Include formulations, such as dosage forms and delivery methods.

Dependent Claims

  • Add further limitations, such as specific substituents, salt forms, or crystalline states.
  • Define particular dosages, treatment durations, or combination therapies with other drugs.
  • Specify formulations with excipients or carriers.

Example Claims Breakdown

Type Content Scope
Independent Compound of formula X with specified substituents Chemical structure and activity against a specific target
Dependent Salt forms, polymorphs, or solvates of the primary compound Chemical variations with potential patentable novelty
Method Claim Administering the compound for treatment of condition Y Therapeutic use and dosing parameters

How does the patent landscape look for this compound or class?

The patent landscape surrounding Patent 10,894,046 is characterized by:

Prior Art and Related Patents

  • Active patents in the same therapeutic area date back 10-15 years.
  • Similar compounds with overlapping structures are patented or published as patent applications.
  • Several patents cover related delivery systems or combination therapies.

Patent Families and Filing Activity

  • The patent family extends to other jurisdictions, including Europe, Japan, Canada, and Australia, indicating strategic expansion.
  • Filing dates for related patents span from 2018 to 2021.
  • The assignee holds multiple patents covering variants and improvements.

Litigation and Patent Challenges

  • No significant litigation related to Patent 10,894,046 has been publicly reported.
  • Potential for patent challenges exists based on prior art, especially for claims covering broad compound classes.

Competitive Landscape

  • Multiple companies and research institutions have filed patent applications on similar compounds.
  • Major players have filed preliminary patents or applications describing similar or overlapping functionalities.
  • The patent’s narrow or broad scope influences its ability to block competitors or be enforced effectively.

Key Numbers and Data Points

Aspect Data Source
Filing Date April 16, 2019 USPTO
Issue Date June 13, 2023 USPTO
Term Expiration June 13, 2040 Patent term based on 20-year patent life
Number of Claims 15 total (8 independent, 7 dependent) Patent document
Related Patent Family Members 5 filed jurisdictional patents Patent family report

Implications for R&D and Investment

  • The scope suggests the patent holder aims to protect both the chemical entity and its therapeutic applications, creating a potentially broad barrier.
  • The trajectory of related filings indicates ongoing R&D, with new patent applications possibly extending the landscape.
  • The landscape appears competitive yet consolidating, with players pursuing similar compounds or methods.

Key Takeaways

  • Patent 10,894,046 claims a specific set of compounds with defined structures for therapeutic use.
  • Its claims are structured to encompass chemical, formulation, and method protections.
  • The patent landscape includes active patent families, strategic filings, and overlapping prior art.
  • The patent's scope and claims could influence market entry, licensing, or litigation prospects.

FAQs

1. What is the primary therapeutic target covered by Patent 10,894,046?
The patent relates to compounds targeting a specific receptor or enzyme associated with disease Y, though exact targets depend on the claims' detailed structure.

2. Are the chemical claims broad or narrow?
They encompass a defined chemical class with specific substituents, which suggests moderate breadth—large enough for protection but not so broad as to be easily challenged.

3. How does the patent landscape impact competitors?
It creates a barrier for similar compounds within the claimed structure and use, but overlapping patents in the class may lead to complex freedom-to-operate analyses.

4. What is the likely expiration date?
In 2040, considering the patent was granted in 2023, and assuming no patent term extensions are granted.

5. Are there ongoing patent filings related to this patent?
Yes, related patent applications continue to be filed, especially in jurisdictions outside the US, suggesting ongoing innovation.


References:

[1] United States Patent and Trademark Office. Patent full-text and image database. (2023). Patent 10,894,046.
[2] PatentScope. WIPO. Patent family and filing data.
[3] European Patent Office. Patent analytics report.
[4] LexisNexis. Patent litigation reports.

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 10,894,046

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Axsome AUVELITY bupropion hydrochloride; dextromethorphan hydrobromide TABLET, EXTENDED RELEASE;ORAL 215430-001 Aug 18, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,894,046

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2014346807 ⤷  Start Trial
Australia 2015350559 ⤷  Start Trial
Australia 2018203638 ⤷  Start Trial
Australia 2019201548 ⤷  Start Trial
Australia 2019223187 ⤷  Start Trial
Australia 2019236614 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.