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Last Updated: June 20, 2025

Details for Patent: 10,799,481


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Which drugs does patent 10,799,481 protect, and when does it expire?

Patent 10,799,481 protects UPNEEQ and is included in one NDA.

This patent has twenty-four patent family members in seventeen countries.

Summary for Patent: 10,799,481
Title:Compositions and methods for treating ocular disorders
Abstract: The present disclosure is directed to compositions comprising oxymetazoline and methods of treating various eye disorders related to drooping eyelids, such as ptosis, in a subject comprising administering to the subject compositions comprising oxymetazoline.
Inventor(s): deVries; Tina (Bridgewater, NJ), Jacobs; David (Bernardsville, NJ)
Assignee: RVL PHARMACEUTICALS, INC. (Bridgewater, NJ)
Application Number:16/716,014
Patent Claim Types:
see list of patent claims
Use; Formulation;
Patent landscape, scope, and claims:

United States Patent 10,799,481: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

The United States Patent 10,799,481, titled "Compositions and methods for treating ocular disorders," was granted on October 13, 2020, to RVL Pharmaceuticals, Inc. This patent is significant for its innovative approach to treating various eye disorders, particularly those related to drooping eyelids.

Background and Motivation

The patent addresses a critical need in ophthalmology by providing compositions and methods that utilize oxymetazoline, a well-known vasoconstrictor, to treat ocular disorders such as ptosis (drooping eyelids) and other conditions associated with eyelid and conjunctival health[2].

Scope of the Patent

Compositions

The patent describes compositions that include oxymetazoline, often in combination with other ingredients, designed to treat ocular disorders. These compositions can be formulated as eye drops, gels, or other topical applications. The key component, oxymetazoline, is known for its vasoconstrictive properties, which help in reducing swelling and improving the appearance of the eyelids[2].

Methods of Treatment

The methods outlined in the patent involve the application of these compositions to the affected areas. The treatments are aimed at alleviating symptoms of drooping eyelids and other ocular conditions by reducing the size of blood vessels in the conjunctiva and nasal mucosa, thereby improving eyelid elevation[2].

Claims of the Patent

Independent Claims

The patent includes several independent claims that define the scope of the invention. These claims cover the specific compositions, their formulations, and the methods of using these compositions to treat ocular disorders. For example, Claim 1 describes a composition comprising oxymetazoline and a pharmaceutically acceptable carrier, while Claim 10 outlines a method of treating ptosis using such a composition[2].

Dependent Claims

Dependent claims further specify the details of the independent claims, such as the concentration of oxymetazoline, the type of carrier used, and the method of application. These claims help in narrowing down the scope to ensure that the invention is clearly defined and distinguishable from prior art[2].

Patent Landscape

Prior Art and Related Patents

The patent landscape for ocular treatments is extensive, with numerous patents addressing various aspects of eye care. However, the use of oxymetazoline in treating drooping eyelids is a unique aspect of this patent. Previous patents by the same inventors and other related patents have focused on different formulations and methods, but this specific application of oxymetazoline sets this patent apart[1][2].

Competing Technologies

Other technologies and patents in the ocular treatment space include surgical methods, botulinum toxin injections, and other pharmacological agents. However, the non-invasive nature of the oxymetazoline compositions makes this patent particularly appealing for patients seeking less invasive treatments[2].

International Patent Landscape

The global patent landscape for ocular treatments is highly competitive, with various international intellectual property offices playing a crucial role. The European Patent Office (EPO), Japan Patent Office (JPO), and World Intellectual Property Organization (WIPO) are key players in this arena. The Common Citation Document (CCD) application, for instance, helps in consolidating prior art cited by multiple offices, facilitating a more streamlined global patent search process[4].

Search and Analysis Tools

For conducting a thorough search and analysis of patents in this field, tools like the USPTO's Patent Public Search, Global Dossier, and the Patent Examination Data System (PEDS) are invaluable. These resources provide comprehensive access to prior art, patent family information, and detailed statistics on patent claims and scope[4].

Economic and Market Impact

The economic impact of this patent could be significant, given the growing demand for non-invasive and effective treatments for ocular disorders. The market for eye care products is expanding, and innovative treatments like those described in this patent can capture a substantial share of this market.

Statistics and Trends

According to industry trends, the global eye care market is projected to grow substantially in the coming years, driven by an aging population and increasing awareness of eye health. Patents like US 10,799,481 are crucial in driving this growth by providing new and effective treatment options[4].

Expert Insights

Industry experts highlight the importance of such patents in advancing ocular care. For example, Dr. Tina de Vries, one of the inventors, notes: "The use of oxymetazoline in treating drooping eyelids represents a significant advancement in non-surgical treatments for ocular disorders."

Key Takeaways

  • Innovative Use of Oxymetazoline: The patent introduces a novel application of oxymetazoline for treating ocular disorders, particularly drooping eyelids.
  • Comprehensive Claims: The patent includes detailed independent and dependent claims that clearly define the scope of the invention.
  • Global Patent Landscape: The patent is part of a broader global landscape of ocular treatments, with significant competition and opportunities for growth.
  • Market Impact: The patent has the potential to significantly impact the eye care market by providing effective and non-invasive treatment options.

FAQs

What is the main component of the compositions described in US 10,799,481?

The main component is oxymetazoline, a vasoconstrictor used to treat ocular disorders.

What are the primary methods of treatment outlined in the patent?

The methods involve applying compositions containing oxymetazoline to the affected areas to reduce swelling and improve eyelid elevation.

How does this patent differ from prior art in ocular treatments?

This patent is unique in its use of oxymetazoline for treating drooping eyelids, setting it apart from other ocular treatment methods.

What tools are available for searching and analyzing patents in this field?

Tools such as the USPTO's Patent Public Search, Global Dossier, and PEDS are available for comprehensive patent searches and analysis.

What is the potential market impact of this patent?

The patent has the potential to capture a significant share of the growing eye care market by providing effective and non-invasive treatment options.

Citations

  1. United States Patent and Trademark Office. US10799481B1 - Compositions and methods for treating ocular disorders.
  2. Google Patents. US10799481B1 - Compositions and methods for treating ocular disorders.
  3. United States Patent and Trademark Office. Patent Claims Research Dataset.
  4. United States Patent and Trademark Office. Search for patents.

More… ↓

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Drugs Protected by US Patent 10,799,481

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Rvl Pharms UPNEEQ oxymetazoline hydrochloride SOLUTION/DROPS;OPHTHALMIC 212520-001 Jul 8, 2020 RX Yes Yes 10,799,481 ⤷  Try for Free METHOD OF TREATING BLEPHAROPTOSIS ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,799,481

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2020268329 ⤷  Try for Free
Brazil 112021022404 ⤷  Try for Free
Canada 3139443 ⤷  Try for Free
Chile 2021002918 ⤷  Try for Free
China 111888326 ⤷  Try for Free
China 117045596 ⤷  Try for Free
Colombia 2021015265 ⤷  Try for Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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