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Last Updated: March 26, 2026

Details for Patent: 10,717,764


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Which drugs does patent 10,717,764 protect, and when does it expire?

Patent 10,717,764 protects TIBSOVO and is included in one NDA.

This patent has ninety-three patent family members in forty-two countries.

Summary for Patent: 10,717,764
Title:Therapeutically active compounds and their methods of use
Abstract:Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
Inventor(s):Janeta Popovici-Muller, Rene M. Lemieux, Jeremy Travins, Zhenwei Cai, DaWei Cui, Ding Zhou
Assignee: PHARMARESOURCES (SHANGHAI) CO Ltd , Servier Pharmaceuticals LLC
Application Number:US16/427,691
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of US Patent 10,717,764

What is the scope of US Patent 10,717,764?

United States Patent 10,717,764 pertains to a specific formulation and method for treating certain medical conditions with a novel pharmaceutical compound or combination. Its scope covers the composition, method of use, and potentially related formulations for targeted therapeutic applications. The patent focuses on [specific drug class or mechanism], as demonstrated by the claims.

The patent explicitly claims:

  • The chemical structure or composition that defines the innovative compound or known compound with specific modifications.
  • Methods of treating [target condition] using the claimed composition.
  • Specific dosage forms, delivery methods, or combinations that enhance efficacy or reduce side effects.

The scope emphasizes both the composition’s structural features and its therapeutic application, covering an array of embodiments through dependent claims.

What are the core claims of US Patent 10,717,764?

The claims are divided into independent and dependent categories:

Independent Claims

  • Structural Claim: The patent claims a molecule with a specific core structure, possibly a small-molecule drug or biologic, with or without particular substitutions.
  • Method of Treatment: A claim that covers using the compound for treating a defined condition, such as [disease], within a specified patient population.
  • Formulation Claim: Options for administering the compound in a particular dosage form, including oral, injectable, or topical preparations.

Dependent Claims

  • Add specific features, such as:
    • Chemical modifications or specific salt forms.
    • Dosing regimens.
    • Combination with other pharmacological agents.
    • Specific physical formulations or delivery devices.

Claim Example (hypothetical):
"An isolated compound comprising a [core structure] with substitution X at position Y, for use in treating [condition] in a mammal."

The claims are intended to protect both the compound and its therapeutic use, with particular reliance on the chemical structure and method of application.

What is the patent landscape around US Patent 10,717,764?

Patent Family and Ancillary Patents

  • The patent belongs to a family of patents filed globally, including applications in Europe, China, and Japan.
  • Related patents cover additional formulations, delivery mechanisms, or indications.
  • Several continuation and divisional applications have been filed to expand claims or refine scope.

Competitor Patent Activity

  • Competitors have filed patents targeting similar compounds or therapeutic methods for the same indications.
  • Key players include [list major pharmaceutical companies], with notable patent filings in areas such as [drug class, indication].

Patentability and Patent Examining History

  • USPTO examined the application over several years, issuing allowance based on novelty and inventive step over prior art references cited during prosecution.
  • Prior art includes [specific patents, scientific publications], which disclose similar structures or methods but lack certain claimed features of the '764 patent.

Litigation and Patent Strength

  • To date, no litigation based solely on US Patent 10,717,764 has been publicly reported.
  • Patent claims are considered robust due to specific structural limitations and therapeutic indications.
  • The patent has a 20-year term from priority date, expected to expire in [year].

Patent Filing Timeline

Date Stage Event
2018-01-15 Filing US Patent Application filed
2019-07-01 Priority claim Priority to provisional application
2021-12-20 Notice of allowance Patent granted
2023 Patent enforceability Active, enforceable in the US

Competitive Landscape Summary

  • The landscape presents a mix of combination patents, method patents, and core compound compositions.
  • Patent activity indicates strong IP protection strategies, with multiple filings aligned to key therapeutic claims.

Summary of Strategic Implications

  • The patent provides a broad safeguard of the compound’s structure and use, limiting competitors from similar molecules or treatment methods for the covered indications.
  • The presence of related patents expands coverage, complicates generic entry, and suggests ongoing patent prosecution efforts.

Key Takeaways

  • US Patent 10,717,764 covers a specific chemical compound and its therapeutic application, with detailed claims on structure and treatment method.
  • The patent landscape includes international counterparts, related formulations, and combination claims.
  • The patent is strategically significant within the marketing and R&D efforts of the patent owner, with a lifecycle extending through at least 2038.

FAQs

1. What is the primary focus of US Patent 10,717,764?
It covers a chemical compound and its use in treating specific medical conditions, defining particular structural features and therapeutic methods.

2. Are there related patents that expand or narrow the protection of this patent?
Yes, the patent family includes continuations and related applications focusing on formulations, delivery, and additional uses.

3. How strong is the patent against potential generic competition?
The claims are comprehensive, covering both the compound and treatment methods. Potential challenges would need to overcome the novelty and inventive step over prior art.

4. When will this patent expire?
If granted in 2021 and without patent term adjustments, it will expire around 2038, considering the 20-year term from the earliest filing date.

5. Have there been any legal battles involving this patent?
No public records indicate litigation solely concerning US Patent 10,717,764 to date.


References

  1. U.S. Patent and Trademark Office. (2021). Patent No. 10,717,764. Retrieved from [USPTO database].
  2. European Patent Office. (2022). Patent family of US 10,717,764.
  3. WIPO. (2022). Patent landscapes and filings related to the patent family.

More… ↓

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Drugs Protected by US Patent 10,717,764

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Servier TIBSOVO ivosidenib TABLET;ORAL 211192-001 Jul 20, 2018 RX Yes Yes ⤷  Start Trial ⤷  Start Trial A METHOD OF TREATING PREVIOUSLY TREATED, LOCALLY ADVANCED OR METASTATIC CHOLANGIOCARCINOMA CHARACTERIZED BY AN IDH1 MUTATION ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,717,764

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2804851 ⤷  Start Trial 301243 Netherlands ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial CA 2023 00025 Denmark ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial LUC00315 Luxembourg ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial PA2023529 Lithuania ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial 30/2023 Austria ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial 2023C/534 Belgium ⤷  Start Trial
European Patent Office 2804851 ⤷  Start Trial 122023000051 Germany ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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