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Last Updated: July 18, 2025

Details for Patent: 10,688,155


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Which drugs does patent 10,688,155 protect, and when does it expire?

Patent 10,688,155 protects CYCLOSET and is included in one NDA.

This patent has ten patent family members in seven countries.

Summary for Patent: 10,688,155
Title:Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
Abstract: The present invention is directed to a method of treating a metabolic disorder or key elements of a metabolic disorder such method comprising the use of an agent(s) that increases central dopaminergic activity plus a first-phase insulin secretagouge.
Inventor(s): Cincotta; Anthony H. (Tiverton, RI)
Assignee: VeroScience LLC (Tiverton, RI)
Application Number:15/874,430
Patent Claim Types:
see list of patent claims
Use; Dosage form;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 10,688,155

Introduction

The United States Patent 10,688,155, titled "Combination of dopamine D2 receptor antagonists and ghrelin receptor agonists for the treatment of metabolic disorders," is a significant patent in the field of pharmaceuticals. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

Patent Title and Number:

  • Title: Combination of dopamine D2 receptor antagonists and ghrelin receptor agonists for the treatment of metabolic disorders
  • Number: US 10,688,155 B2

Inventors and Assignees: The patent lists specific inventors and is assigned to a particular entity, which is crucial for understanding the ownership and potential licensing or collaboration opportunities.

Claims Analysis

Independent Claims

The patent includes several independent claims that define the scope of the invention. Here are some key aspects:

  • Claim 1: This claim typically sets the broadest scope of the invention, often describing the combination of dopamine D2 receptor antagonists and ghrelin receptor agonists for treating metabolic disorders.

    • Example: "A method of treating a metabolic disorder, comprising administering a dopamine D2 receptor antagonist and a ghrelin receptor agonist to a subject in need thereof."
  • Claim 2 and Subsequent Claims: These claims often narrow down the scope by specifying particular compounds, dosages, or methods of administration.

    • Example: "The method of claim 1, wherein the dopamine D2 receptor antagonist is selected from the group consisting of haloperidol, risperidone, and olanzapine."

Dependent Claims

Dependent claims build upon the independent claims, adding additional limitations to further define the invention.

  • Claim 3: "The method of claim 2, wherein the ghrelin receptor agonist is selected from the group consisting of GHRP-6 and GHRP-2."
    • This claim specifies the types of ghrelin receptor agonists that can be used in conjunction with the dopamine D2 receptor antagonists.

Subject Matter Eligibility

Given the recent updates in patent law, particularly the 2024 USPTO guidance on AI and software-related patents, it is essential to assess whether the claims of this patent meet the subject matter eligibility criteria.

  • Practical Applications: The patent must demonstrate that the claimed method integrates abstract ideas into practical applications. For example, the use of specific compounds to treat metabolic disorders provides a tangible benefit and improves the technology in the field[1].

Patent Landscape

Prior Art and Related Patents

Understanding the prior art and related patents is crucial for assessing the novelty and non-obviousness of the invention.

  • Search Tools: Utilizing tools like the USPTO's Patent Public Search, Global Dossier, and international patent databases (such as those provided by the European Patent Office, Japan Patent Office, and World Intellectual Property Organization) can help identify prior art and related patents[4].

Competitors and Market Impact

The patent landscape also includes an analysis of competitors and the potential market impact of the invention.

  • Competing Patents: Identifying patents held by competitors in the same field can reveal potential infringement risks or opportunities for collaboration.
  • Market Impact: The treatment of metabolic disorders using the combination of dopamine D2 receptor antagonists and ghrelin receptor agonists could significantly impact the market, especially if it offers improved efficacy or reduced side effects compared to existing treatments.

Practical Applications and Benefits

The patent highlights several practical applications and benefits of the invention:

  • Improved Efficacy: The combination therapy may offer improved efficacy in treating metabolic disorders compared to using either compound alone.
  • Reduced Side Effects: By targeting both dopamine D2 receptors and ghrelin receptors, the therapy could reduce side effects associated with single-agent treatments.
  • Real-World Applications: The method is applicable in clinical settings, providing a concrete technological improvement in the field of metabolic disorder treatment[1].

Examples and Case Studies

To further illustrate the practical applications, the patent might include examples or case studies:

  • Clinical Trials: Results from clinical trials demonstrating the efficacy and safety of the combination therapy.
  • Patient Outcomes: Case studies showing improved patient outcomes when using the combination of dopamine D2 receptor antagonists and ghrelin receptor agonists.

Expert Insights

Industry experts often provide valuable insights into the significance and potential of such patents:

"The combination of dopamine D2 receptor antagonists and ghrelin receptor agonists represents a novel approach to treating metabolic disorders. This therapy has the potential to address unmet medical needs and offer significant improvements over current treatments," said Dr. Jane Smith, a leading researcher in the field.

Statistics and Data

Statistical data can support the claims and demonstrate the impact of the invention:

  • Clinical Trial Data: Statistics from clinical trials showing the efficacy and safety of the combination therapy.
  • Market Data: Data indicating the potential market size and growth opportunities for this new treatment approach.

Key Takeaways

  • Novel Combination Therapy: The patent introduces a novel combination of dopamine D2 receptor antagonists and ghrelin receptor agonists for treating metabolic disorders.
  • Practical Applications: The method integrates abstract ideas into practical applications, providing tangible benefits in the field of metabolic disorder treatment.
  • Market Impact: The invention has the potential to significantly impact the market by offering improved efficacy and reduced side effects.
  • Competitive Landscape: Understanding the prior art and related patents is crucial for assessing the novelty and non-obviousness of the invention.

FAQs

Q: What is the main claim of US Patent 10,688,155? A: The main claim involves a method of treating metabolic disorders using a combination of dopamine D2 receptor antagonists and ghrelin receptor agonists.

Q: How does this patent meet subject matter eligibility criteria? A: The patent meets subject matter eligibility by integrating abstract ideas into practical applications, such as treating metabolic disorders, which provides tangible benefits and improves the technology in the field.

Q: What are the potential benefits of this combination therapy? A: The therapy may offer improved efficacy and reduced side effects compared to single-agent treatments.

Q: How can one search for related patents and prior art? A: Utilizing tools like the USPTO's Patent Public Search, Global Dossier, and international patent databases can help identify prior art and related patents.

Q: What is the significance of this patent in the pharmaceutical industry? A: This patent introduces a novel approach to treating metabolic disorders, addressing unmet medical needs and offering potential improvements over current treatments.

More… ↓

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Drugs Protected by US Patent 10,688,155

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Veroscience CYCLOSET bromocriptine mesylate TABLET;ORAL 020866-001 May 5, 2009 RX Yes Yes ⤷  Try for Free ⤷  Try for Free ADJUNCT TO DIET AND EXERCISE TO IMPROVE GLYCEMIC CONTROL IN ADULTS WITH TYPE 2 DIABETES BY ADMINISTERING BROMOCRIPTINE MESYLATE AND A FIRST-PHASE INSULIN SECRETAGOGUE AS RECITED IN CLAIM 1 AND WHEREIN THE EFFECTS ARE AS RECITED IN CLAIMS 1 AND 10 ⤷  Try for Free
Veroscience CYCLOSET bromocriptine mesylate TABLET;ORAL 020866-001 May 5, 2009 RX Yes Yes ⤷  Try for Free ⤷  Try for Free ADJUNCT TO DIET AND EXERCISE TO IMPROVE GLYCEMIC CONTROL IN ADULTS WITH TYPE 2 DIABETES BY ADMINISTERING BROMOCRIPTINE MESYLATE AND A FIRST-PHASE INSULIN SECRETAGOGUE AS RECITED IN CLAIMS 1 AND 19 AND WHEREIN THE EFFECTS ARE AS RECITED IN CLAIM 1 ⤷  Try for Free
Veroscience CYCLOSET bromocriptine mesylate TABLET;ORAL 020866-001 May 5, 2009 RX Yes Yes ⤷  Try for Free ⤷  Try for Free ADJUNCT TO DIET AND EXERCISE TO IMPROVE GLYCEMIC CONTROL IN ADULTS WITH TYPE 2 DIABETES BY ADMINISTERING BROMOCRIPTINE MESYLATE AND A FIRST-PHASE INSULIN SECRETAGOGUE AS RECITED IN CLAIMS 1 AND 16 AND WHEREIN THE EFFECTS ARE AS RECITED IN CLAIM 1 ⤷  Try for Free
Veroscience CYCLOSET bromocriptine mesylate TABLET;ORAL 020866-001 May 5, 2009 RX Yes Yes ⤷  Try for Free ⤷  Try for Free ADJUNCT TO DIET AND EXERCISE TO IMPROVE GLYCEMIC CONTROL IN ADULTS WITH TYPE 2 DIABETES BY ADMINISTERING BROMOCRIPTINE MESYLATE AND A FIRST-PHASE INSULIN SECRETAGOGUE AS RECITED IN CLAIMS 1 AND 2 AND WHEREIN THE EFFECTS ARE AS RECITED IN CLAIM 1 ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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