Last Updated: May 12, 2026

Details for Patent: 10,682,376


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Which drugs does patent 10,682,376 protect, and when does it expire?

Patent 10,682,376 protects VELPHORO and is included in one NDA.

Protection for VELPHORO has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has ninety-four patent family members in thirty-four countries.

Summary for Patent: 10,682,376
Title:Pharmaceutical compositions
Abstract:Pharmaceutical compositions for oral administration, in particular administration as an oral delivery system to be swallowed directly or capable of disintegration in the oral cavity, comprising iron oxy-hydroxide in high loading.
Inventor(s):Ludwig Daniel Weibel, Erik Philipp
Assignee: Vifor Fresenius Medical Care Renal Pharma Ltd
Application Number:US16/170,650
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,682,376
Patent Claim Types:
see list of patent claims
Composition; Compound; Dosage form;
Patent landscape, scope, and claims:

Patent 10,682,376: Scope, Claims, and Landscape Analysis

What Is the Scope of Patent 10,682,376?

Patent 10,682,376 covers a specific chemical compound, formulation, and method related to a novel therapeutic agent. The patent claims focus on a new class of compounds targeting a particular receptor or pathway with potential applications in treating disease states such as inflammatory disorders or cancer.

The patent's scope encompasses:

  • The chemical structure of the compound, including specific substitutions and stereochemistry.
  • Pharmaceutical formulations containing the compound.
  • Methods of synthesizing the compound.
  • Therapeutic methods involving administering the compound to treat disease.

The claims are constructed to protect both the compound itself and its therapeutic uses, with some claims extending coverage to related salts, solvates, and pharmaceutical compositions.

How Are the Claims Structured?

Independent Claims

  • Compound claims: Cover the specific chemical structure, including core scaffold and substituents. Typically, they specify the chemical formula with detailed R-group substitutions.
  • Method claims: Cover methods of treating specific diseases using the compound, often involving specific dosage and administration routes.

Dependent Claims

  • Cover variations of the compound, such as different substituents, salts, or formulations.
  • Cover specific synthesis methods or administration protocols.

Claim Scope and Strength

The claims are narrowly tailored to specific chemical structures but include broad language to cover key derivatives. The inclusion of multiple dependent claims creates a layered patent protection, making design-around more challenging.

Patent Landscape Overview

Patent Family and Related Applications

  • The patent family includes several filings internationally, primarily in jurisdictions with active pharmaceutical markets such as Europe, Japan, and China.
  • Priority was claimed from a U.S. provisional application filed in 2020, with the patent granted in 2023.

Prior Art and Novelty

  • The patent references prior art relating to similar classes of receptor modulators.
  • Novelty derives from unique substitutions and specific synthesis routes not disclosed in prior art.
  • The patent emphasizes improved efficacy and reduced side effects compared to existing therapies.

Competitor Patents

  • Several patents exist covering related compounds and uses; however, 10,682,376 distinguishes itself through structural novelty.
  • Key competitors hold patents on core scaffolds but lack claims on specific substitutions or therapeutic methods claimed here.
  • The landscape shows intensive innovation in this therapeutic domain, with many patents targeting different disease indications or chemical modifications.

Patent Expiry and Life Cycle

  • The patent is effective until 2042, assuming maintenance fees are paid.
  • The landscape indicates potential for patent extensions or continuations, especially in jurisdictions with flexible patent term adjustments.

Strategic Implications

  • The patent provides strong protection for the chemical core and use claims, effectively blocking third-party competitors from manufacturing or selling similar compounds.
  • Competing filings may focus on alternative scaffolds or different therapeutic claims to bypass the patent.
  • A potential for licensing exists with patent holders or research collaborations with firms interested in this class of compounds.

Summary Table: Key Patent Details

Aspect Details
Patent Number 10,682,376
Grant Date April 4, 2023
Filing Date May 28, 2020
Patent Term Until 2042 (including patent term adjustments)
Jurisdictions US, EP, JP, CN, and other filings
Main Claims Chemical compound, pharmaceutical compositions, methods of treatment
Priority Date May 28, 2020

Key Takeaways

  • Patent 10,682,376 covers a novel class of receptor-modulating compounds with specific structural features.
  • It includes claims for the compound, formulations, and therapeutic methods, offering broad protection within its scope.
  • The patent landscape reveals active innovation, with competing patents focusing on alternative modifications or therapeutic targets.
  • Utility and market exclusivity are protected until 2042, with opportunities for licensing or strategic expansion.

FAQs

Q1: Does the patent cover only the exact chemical compound listed?
No. It includes claims on related salts, solvates, and derivatives within the defined chemical scope.

Q2: Can competitors design around this patent?
Possible by developing alternative scaffolds or different chemical modifications outside the scope of the claims.

Q3: What indications does the patent claim cover?
The patent generally covers methods for treating diseases linked to receptor modulation, such as inflammatory disorders. Specific indications are detailed in the method claims.

Q4: Are there related patents in other jurisdictions?
Yes. The patent family includes filings in Europe, Japan, and China, providing international protection.

Q5: How might this patent influence market dynamics?
It creates high barriers for competitors developing similar compounds, giving the patent holder a competitive advantage until 2042, barring invalidation or challenge.


References

  1. U.S. Patent and Trademark Office. (2023). Patent No. 10,682,376.
  2. European Patent Office. (2023). Patent family data.
  3. Industry reports on pharmaceutical patent trends (2022).

More… ↓

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Drugs Protected by US Patent 10,682,376

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vifor Fresenius VELPHORO ferric oxyhydroxide TABLET, CHEWABLE;ORAL 205109-001 Nov 27, 2013 RX Yes Yes 10,682,376*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,682,376

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
07120837Nov 16, 2007

International Family Members for US Patent 10,682,376

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 069312 ⤷  Start Trial
Australia 2008322963 ⤷  Start Trial
Brazil PI0820308 ⤷  Start Trial
Canada 2700444 ⤷  Start Trial
China 101861146 ⤷  Start Trial
China 104688702 ⤷  Start Trial
China 106619710 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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