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Last Updated: June 20, 2025

Details for Patent: 10,550,126


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Which drugs does patent 10,550,126 protect, and when does it expire?

Patent 10,550,126 protects RINVOQ and is included in one NDA.

This patent has forty-nine patent family members in thirteen countries.

Summary for Patent: 10,550,126
Title:Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2- -trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-.alpha.]pyrrolo[2,3-e]pyrazin-8-yl)-N-(- 2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis and atopic dermatitis), kits, methods of synthesis, and products-by-process.
Inventor(s): Pangan; Aileen L. (La Grange, IL), Teixeira; Henrique D. (Green Oaks, IL), Mohamed; Mohamed-Eslam F. (Gurnee, IL), Othman; Ahmed A. (Libertyville, IL), Klunder; Ben (Ludwigshafen, DE)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:15/954,039
Patent Claim Types:
see list of patent claims
Use; Dosage form;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 10,550,126

Introduction

Understanding the scope and claims of a patent is crucial for assessing its value, identifying potential infringements, and navigating the intellectual property landscape. This article will delve into the details of United States Patent 10,550,126, focusing on its claims, scope, and the broader patent landscape.

Overview of the Patent

US10550126B2 titled "Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof" is a patent that describes specific chemical processes and compounds. Here is a brief overview:

  • Publication Number: US10550126B2
  • Authority: United States
  • Prior Art Keywords: Compound, freebase, solid state, formula
  • Legal Status: Active[4].

Claims Analysis

Independent and Dependent Claims

The patent includes both independent and dependent claims. Independent claims define the broadest scope of the invention, while dependent claims narrow down the scope by adding additional limitations.

  • Independent Claims: These claims outline the core invention, such as the specific chemical compounds and their preparation processes. For example, Claim 1 might describe the general process for preparing the compound, while subsequent independent claims might detail different aspects or variations of the process.
  • Dependent Claims: These claims build upon the independent claims by adding specific details or limitations. For instance, a dependent claim might specify a particular solvent used in the preparation process or a specific temperature range.

Claim Scope and Breadth

The scope of the claims is a critical factor in determining the patent's protection and potential infringement. Here are some key points:

  • Claim Length and Count: Research suggests that narrower claims, as measured by independent claim length and count, are associated with a higher probability of grant and a shorter examination process. This patent's claims should be analyzed in this context to understand their breadth and clarity[5].
  • Specificity: The claims must be specific enough to define the invention clearly but broad enough to cover the intended scope. For chemical patents, this often involves detailed descriptions of the compounds and their synthesis processes.

Scope of the Patent

Chemical Compounds and Processes

The patent focuses on the preparation of a specific compound, (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, and its solid state forms.

  • Synthesis Processes: The patent details various methods for synthesizing the compound, including the use of specific reagents, solvents, and reaction conditions.
  • Solid State Forms: The patent also covers different solid state forms of the compound, which can be crucial for pharmaceutical applications due to their impact on stability, solubility, and bioavailability.

Applications and Uses

The compound described in the patent is under clinical trials for treating conditions such as rheumatoid arthritis and atopic dermatitis. This indicates the patent's scope extends beyond the chemical synthesis to potential therapeutic applications.

Patent Landscape Analysis

Related Patents and Prior Art

To understand the patent's position within the broader patent landscape, it is essential to identify related patents and prior art.

  • Global Dossier: Using tools like the Global Dossier, one can access the file histories of related applications from participating IP Offices, which helps in identifying the patent family and related applications[1].
  • Common Citation Document (CCD): The CCD consolidates prior art cited by all participating offices for the family members of a patent application, providing a comprehensive view of the prior art landscape[1].

Competitor Patents

Analyzing competitor patents in the same field can reveal gaps and opportunities.

  • Patent Analytics: Tools like Claim Coverage Matrix and Claim Charts can help categorize patents by claims and scope concepts, making it easier to identify where competitors have coverage and where there are gaps[3].

Claim Coverage and Scope Concepts

Claim Coverage Matrix

A Claim Coverage Matrix is a powerful tool for understanding which patents and claims are actively protecting the intellectual property.

  • Scope Concepts: Categorizing patents by overarching scope concepts helps in filtering and analyzing large numbers of patent claims. This method is particularly useful for identifying high-value, medium-value, and low-value claims[3].

Interactive Claim Charts

Interactive claim charts generated by tools like ClaimScape® software can be reviewed by technical experts to determine the applicability of scope concepts to target products or methods.

  • Future Design Opportunities: These charts can highlight areas where there are gaps in current coverage and indicate future design opportunities[3].

Practical Implications

Licensing and Litigation

The clarity and breadth of the claims can significantly impact licensing and litigation costs. Narrower, clearer claims are generally less likely to be challenged and can reduce the risk of costly litigation.

Innovation Incentives

The quality of the patent, as measured by its scope and claim clarity, can influence innovation incentives. Patents with overly broad or unclear claims may diminish these incentives due to increased licensing and litigation costs[5].

Key Takeaways

  • Claims Analysis: Understanding the independent and dependent claims is crucial for determining the patent's scope and potential infringement.
  • Scope of the Patent: The patent covers specific chemical compounds, their synthesis processes, and solid state forms, with applications in pharmaceuticals.
  • Patent Landscape: Analyzing related patents and prior art using tools like Global Dossier and CCD is essential for positioning the patent within the broader landscape.
  • Competitor Analysis: Using patent analytics tools to identify gaps and opportunities in competitor patents can be highly beneficial.
  • Practical Implications: The clarity and breadth of claims can impact licensing, litigation, and innovation incentives.

FAQs

  1. What is the main subject of United States Patent 10,550,126?

    • The main subject is the preparation of the compound (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and its solid state forms.
  2. How can one analyze the scope of the claims in a patent?

    • Analyzing the scope involves examining the independent and dependent claims, using metrics such as claim length and count, and understanding the specificity and breadth of the claims.
  3. What tools can be used to analyze the patent landscape?

    • Tools such as the Global Dossier, Common Citation Document (CCD), and patent analytics software like ClaimScape® can be used to analyze the patent landscape.
  4. Why is claim clarity important?

    • Claim clarity is important because it affects the patent's protection, potential infringement, licensing costs, and litigation risks. Clearer claims generally reduce these risks and costs.
  5. How can patent analytics help in managing intellectual property?

    • Patent analytics can help by categorizing patents by claims and scope concepts, identifying gaps and opportunities, and providing interactive claim charts to review coverage and future design options.

Sources

  1. USPTO - Search for patents. Retrieved from https://www.uspto.gov/patents/search
  2. Unified Patents - US-20170266289-A1. Retrieved from https://portal.unifiedpatents.com/patents/patent/US-20170266289-A1
  3. SLWIP - Patent Analytics. Retrieved from https://www.slwip.com/services/patent-analytics/
  4. Google Patents - US10550126B2. Retrieved from https://patents.google.com/patent/US10550126B2/en
  5. SSRN - Patent Claims and Patent Scope. Retrieved from https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2844964

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Drugs Protected by US Patent 10,550,126

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Abbvie RINVOQ upadacitinib TABLET, EXTENDED RELEASE;ORAL 211675-002 Jan 14, 2022 RX Yes No ⤷  Try for Free ⤷  Try for Free TREATMENT OF ADULTS AND PEDIATRIC PATIENTS 12 YEARS OF AGE AND OLDER WITH REFRACTORY, MODERATE TO SEVERE ATOPIC DERMATITIS WHOSE DISEASE IS NOT ADEQUATELY CONTROLLED WITH OTHER SYSTEMIC DRUG PRODUCTS, OR WHEN USE OF THOSE THERAPIES ARE INADVISABLE ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,550,126

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2016340167 ⤷  Try for Free
Australia 2020359635 ⤷  Try for Free
Australia 2021236570 ⤷  Try for Free
Australia 2023251492 ⤷  Try for Free
Brazil 112018007677 ⤷  Try for Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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