Last Updated: August 9, 2026

Details for Patent: 10,519,146


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Which drugs does patent 10,519,146 protect, and when does it expire?

Patent 10,519,146 protects LUMAKRAS and is included in one NDA.

This patent has seventy-six patent family members in thirty-eight countries.

Summary for Patent: 10,519,146
Title:KRAS G12C inhibitors and methods of using the same
Abstract:Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
Inventor(s):Brian Alan Lanman, Jian Chen, Anthony B. Reed, Victor J. Cee, Longbin Liu, David John KOPECKY, Patricia Lopez, Ryan Paul Wurz, Thomas T. Nguyen, Shon Booker, Nobuko Nishimura, Youngsook Shin, Nuria A. Tamayo, John Gordon Allen, Jennifer Rebecca Allen
Assignee: Amgen Inc
Application Number:US15/984,855
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound;
Patent landscape, scope, and claims:

error: insufficient information

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Recent additions to Drugs Protected by US Patent 10,519,146

These patents are from the daily update and have not yet been integrated into the regular database
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Product Substance Delist Req. Patent Expiration Usecode Patented / Exclusive Use
Amgen Inc LUMAKRAS sotorasib TABLET 214665 May 28, 2021 RX Yes 10,519,146 Y Y ⤷  Start Trial
Amgen Inc LUMAKRAS sotorasib TABLET 214665 Jun 26, 2024 RX Yes 10,519,146 Y Y ⤷  Start Trial
Amgen Inc LUMAKRAS sotorasib TABLET 214665 Jan 20, 2023 RX Yes 10,519,146 Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Type >RLD >Patent No. >Product >Substance >Delist Req. >Patent Expiration >Usecode >Patented / Exclusive Use

Drugs Protected by US Patent 10,519,146

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Amgen Inc LUMAKRAS sotorasib TABLET;ORAL 214665-001 May 28, 2021 RX Yes No 10,519,146 ⤷  Start Trial Y Y ⤷  Start Trial
Amgen Inc LUMAKRAS sotorasib TABLET;ORAL 214665-003 Jun 26, 2024 RX Yes No 10,519,146 ⤷  Start Trial Y Y ⤷  Start Trial
Amgen Inc LUMAKRAS sotorasib TABLET;ORAL 214665-002 Jan 20, 2023 RX Yes Yes 10,519,146 ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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