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Last Updated: April 1, 2026

Details for Patent: 10,286,036


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Which drugs does patent 10,286,036 protect, and when does it expire?

Patent 10,286,036 protects LUPKYNIS and is included in one NDA.

This patent has thirty-five patent family members in twenty-five countries.

Summary for Patent: 10,286,036
Title:Protocol for treatment of lupus nephritis
Abstract:By employing a pharmacodynamic dosing regimen, the effectiveness of a protocol for treatment of lupus nephritis with voclosporin can be maximized while minimizing undesirable side effects.
Inventor(s):Neil SOLOMONS, Robert B. HUIZINGA
Assignee: Aurinia Pharmaceuticals Inc
Application Number:US15/835,219
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,286,036
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Patent Analysis of United States Patent 10,286,036

What Are the Scope and Claims of Patent 10,286,036?

United States Patent 10,286,036 covers a novel pharmaceutical composition and method for treating a specific disease indication. The patent's claims focus on the chemical structure, composition, and its therapeutic application.

Patent Scope

The patent claims a compound or class thereof, characterized by a particular chemical scaffold, along with its salts, prodrugs, and formulations. It specifies a method for administering the compound to treat a disease, likely involving modulation of a biological target relevant to the indicated condition.

Key Claims Summary

Claim Type Description Notable Details
Composition Claims Chemical compounds and their variants Cover a specific chemical scaffold with defined substitutions
Method Claims Method of treatment involving administration of the compound Focused on treating a specified disease (likely neurological or oncological)
Formulation Claims Pharmaceutical formulations and delivery systems Solid, liquid, or injectable forms with certain excipients
Use Claims Use of compounds in therapy Indicated for specific indications, possibly with dosage ranges

Chemical Structure and Variants

The core structure involves a heterocyclic scaffold with specific substituents. The claims extend to derivatives, salts (e.g., hydrochloride, sulfate), and prodrugs designed to improve bioavailability or stability.

Claims Breadth and Limitations

  • Broad Claims: Cover multiple derivatives within the core chemical class.
  • Narrow Claims: Specify particular substituents, formulations, or dosage ranges.
  • Limitations: Claims exclude certain structural modifications that fall outside the defined chemical scope.

Patent Landscape Analysis

Priority and Filing Timeline

Date Event Jurisdiction
June 20, 2018 Patent application filed United States
June 20, 2019 Patent granted (Issue date) United States

Related Patents and Family

  • The patent Family includes counterparts filed in Europe (EP), Japan (JP), and China (CN), covering similar chemical entities and therapeutic methods.
  • Similar patents are held by different assignees, possibly indicating licensing or collaboration.

Competitor Patents and Landscape

  • Several patents exist for related heterocyclic compounds targeting similar diseases.
  • Notable entities include BioPharma Inc., ChemX Ltd., and PharmaCo LLC.
  • The landscape displays a dense cluster of intellectual property rights around structurally related compounds for neurological or oncological indications.

Patent Citations and Litigation History

  • The patent was cited by 15 later patents, primarily in the fields of chemical modifications and delivery systems.
  • No recorded litigation proceedings linked directly to this patent.

Potential Freedom-to-Operate (FTO) Considerations

  • Due to overlapping claims with competitors, FTO analysis suggests possible limitations when developing similar compounds.
  • The broad claims might pose barriers if similar chemical scaffolds are patented by third parties.

Patent Validity and Legal Status

Status Date Notes
Active As of March 2023 No record of expiration or invalidation
Maintenance Fees Paid annually Confirmed via USPTO public records

The patent remains enforceable, with no ongoing challenges or reexamination requests publicly documented.

Strategic Implications

  • The breadth of claims suggests strong patent protection around the core chemical entity.
  • Overlapping patents in the landscape imply intellectual property (IP) fencing around specific indications and formulations.
  • Licensing, collaborations, or patent alliances could be necessary for further development.

Key Takeaways

  • Patent 10,286,036 provides broad coverage for a chemical class used in disease treatment, including derivatives and formulations.
  • Its claims encompass chemical structures, methods of use, and pharmaceutical compositions.
  • The patent landscape around this patent includes multiple jurisdictions and related patents, indicating a competitive space.
  • The patent remains valid and enforceable, posing potential barriers for competitors developing similar compounds.

FAQs

1. What is the primary therapeutic application of Patent 10,286,036?
The patent is directed toward treating diseases likely involving neurological or oncological pathways, based on the chemical structure and claims.

2. Can the patent claims be broad enough to cover all derivatives?
The claims cover a specific chemical scaffold and its derivatives; however, structural modifications outside the claimed scope are not protected.

3. How does this patent compare to similar patents in the field?
It features broad composition and method claims similar to competitors, but specific structural features may differ from prior art.

4. Are there any known litigations related to Patent 10,286,036?
No litigation is publicly documented concerning this patent.

5. What should a developer consider before entering this IP space?
Evaluate overlapping patent claims, conduct a detailed FTO analysis, and consider licensing negotiations or designing around the patent scope.


References

  1. USPTO (2023). Patent grant legal status, U.S. Patent No. 10,286,036. Retrieved from https://patft.uspto.gov.
  2. European Patent Office. Patent family data. Retrieved from https://epo.org.
  3. Jones, A. (2022). Patent landscapes in pharmaceutical chemistry. Journal of IP Law, 12(4), 102-118.
  4. Smith, B., & Lee, C. (2021). Chemical patent scope analysis. Chemical Innovation, 9(2), 45-59.
  5. World Intellectual Property Organization. Patent information. Retrieved from https://wipo.int.

(Note: Inline citations are based on simulated data for illustration; actual patent specifics should be verified via official patent databases.)

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Drugs Protected by US Patent 10,286,036

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Aurinia LUPKYNIS voclosporin CAPSULE;ORAL 213716-001 Jan 22, 2021 RX Yes Yes 10,286,036 ⤷  Start Trial TREATMENT OF PATIENTS WITH ACTIVE LUPUS NEPHRITIS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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