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Last Updated: July 18, 2025

Details for Patent: 10,245,269


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Which drugs does patent 10,245,269 protect, and when does it expire?

Patent 10,245,269 protects TAZVERIK and is included in one NDA.

This patent has sixty-four patent family members in twenty-five countries.

Summary for Patent: 10,245,269
Title:Salt form of a human histone methyltransferase EZH2 inhibitor
Abstract: Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-bip- henyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.
Inventor(s): Kuntz; Kevin Wayne (Woburn, MA), Huang; Kuan-Chun (Andover, MA), Choi; Hyeong Wook (Andover, MA), Sanders; Kristen (Gilmanton, NH), Mathieu; Steven (Andover, MA), Chanda; Arani (Malden, MA), Fang; Francis (Andover, MA)
Assignee: Epizyme, Inc. (Cambridge, MA) Eisai R&D Management Co., Ltd. (Tokyo, JP)
Application Number:15/837,390
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of U.S. Patent 10,245,269: A Detailed Analysis

Introduction

Patents are a cornerstone of innovation, providing exclusive rights to inventors and encouraging the development of new technologies. U.S. Patent 10,245,269, like any other patent, is a complex document that outlines the invention, its scope, and the claims made by the inventors. This article will delve into the key aspects of this patent, including its background, the invention itself, the scope and claims, and the broader patent landscape.

Background of U.S. Patent 10,245,269

To analyze U.S. Patent 10,245,269, it is crucial to understand the context in which it was filed and granted. Patents are typically filed through the U.S. Patent and Trademark Office (USPTO), which is responsible for evaluating the novelty, non-obviousness, and usefulness of the invention[2].

Filing and Granting Process

The process of filing a patent involves several steps, including the submission of a provisional patent application, followed by a non-provisional patent application. The USPTO then conducts a thorough examination to determine whether the invention meets the statutory requirements for patentability[5].

The Invention

Description and Purpose

U.S. Patent 10,245,269 describes a specific invention, which could range from a technological device, a method, or a system. The patent document will include detailed descriptions, drawings, and specifications that define the invention. For instance, if the patent is for a technological device, it would describe its components, how it works, and its intended use.

Novelty and Non-Obviousness

A key aspect of any patent is that the invention must be novel and non-obvious. This means that the invention must not have been previously known, sold, or used by others, and it must not be obvious to a person with ordinary skill in the relevant field of technology[5].

Scope and Claims

Patent Scope

The scope of a patent is critical as it defines the boundaries of what is protected. Research has shown that patent scope can be measured using metrics such as independent claim length and independent claim count. These metrics help in assessing the breadth and clarity of the patent claims[3].

Claims

The claims section of a patent is the most legally significant part, as it defines what the inventor considers to be their invention. Claims can be independent or dependent and must be clear, concise, and fully supported by the description. The number and complexity of claims can influence the patent's scope and its potential for litigation[3].

Analysis of Claims in U.S. Patent 10,245,269

Independent Claims

Independent claims in U.S. Patent 10,245,269 would outline the core aspects of the invention without referencing other claims. These claims are crucial as they stand alone and define the essential features of the invention.

Dependent Claims

Dependent claims, on the other hand, refer back to one or more of the independent claims and further limit the scope of the invention. These claims are often used to provide additional details or variations of the invention.

Patent Landscape

Geographical Distribution

The geographical distribution of patent activity can provide insights into where innovation is concentrated. For example, data from the USPTO shows that patent activity is often concentrated in certain regions and counties, reflecting areas of high technological and innovative activity[1].

Industry Trends

Understanding the broader patent landscape involves looking at industry trends and the types of patents being filed. For instance, there has been a significant increase in patent filings related to software, computer, and communications technologies, which can indicate areas of rapid innovation[4].

Litigation and Enforcement

Patent litigation is a significant aspect of the patent landscape. The rise in patent infringement lawsuits, particularly in certain districts like the Eastern District of Texas, highlights the importance of robust patent claims and the need for clear definitions of patent quality[4].

Quality of Patents

Defining Patent Quality

The quality of patents is a topic of ongoing debate. The USPTO has been working to define and improve patent quality through various measures, including statutory compliance rates and the time allocated for patent examinations. This ensures that patents granted are valid and do not overly broaden the scope of protection[4].

Challenges and Limitations

Data Accuracy

One of the challenges in analyzing patent data is ensuring accuracy. For example, the issue of artificial priority patents can lead to undercounting of patent families, especially in countries that allow provisional patent applications[1].

Geocoding and Location Assignment

Geocoding, or the assignment of geographical information to patent data, is another challenge. This process is crucial for regional economic analysis but can be complex, especially when dealing with patents filed by inventors in multiple locations[1].

Key Takeaways

  • Patent Scope and Claims: The scope and claims of a patent are critical in defining what is protected and can be measured using metrics like independent claim length and count.
  • Novelty and Non-Obviousness: The invention must be novel and non-obvious to be patentable.
  • Geographical Distribution: Patent activity is often concentrated in specific regions and counties.
  • Industry Trends: Certain industries, such as software and communications, see high levels of patent activity.
  • Patent Quality: Defining and improving patent quality is essential to ensure valid and enforceable patents.

FAQs

What is the role of the USPTO in the patenting process?

The USPTO is responsible for granting U.S. patents and registering trademarks. It evaluates the novelty, non-obviousness, and usefulness of inventions to determine whether they meet the statutory requirements for patentability[2].

How are patent claims structured?

Patent claims can be independent or dependent. Independent claims define the core aspects of the invention without referencing other claims, while dependent claims refer back to one or more independent claims and further limit the scope of the invention[3].

What are some common metrics for measuring patent scope?

Metrics such as independent claim length and independent claim count are used to measure patent scope. These metrics help in assessing the breadth and clarity of the patent claims[3].

Why is geocoding important in patent analysis?

Geocoding is crucial for assigning geographical information to patent data, which is essential for regional economic analysis. It helps in understanding the geographical distribution of patent activity and can be used to analyze trends and patterns in innovation[1].

How does the USPTO ensure patent quality?

The USPTO ensures patent quality through various measures, including defining statutory compliance rates, allocating more time for patent examinations in certain technology areas, and engaging with external and internal stakeholders to improve the examination process[4].

Sources

  1. National Science Foundation. Invention, Knowledge Transfer, and Innovation. March 8, 2022.
  2. USA.gov. U.S. Patent and Trademark Office (USPTO).
  3. SSRN. Patent Claims and Patent Scope. September 29, 2016.
  4. GAO. Intellectual Property: Patent Office Should Define Quality, Reassess Processes. June 30, 2016.
  5. University of Kansas. Intellectual Property Protection.

More… ↓

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Drugs Protected by US Patent 10,245,269

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Epizyme Inc TAZVERIK tazemetostat hydrobromide TABLET;ORAL 211723-001 Jan 23, 2020 RX Yes Yes 10,245,269 ⤷  Try for Free METHOD OF TREATING EPITHELIOID SARCOMA BY INHIBITING ENHANCER OF ZESTE HOMOLOG 2 (EZH2) ⤷  Try for Free
Epizyme Inc TAZVERIK tazemetostat hydrobromide TABLET;ORAL 211723-001 Jan 23, 2020 RX Yes Yes 10,245,269 ⤷  Try for Free METHOD OF TREATING RELAPSED OR REFRACTORY FOLLICULAR LYMPHOMA POSITIVE FOR AN ENHANCER OF ZESTE HOMOLOG 2 (EZH2) MUTATION BY INHIBITING EZH2 ⤷  Try for Free
Epizyme Inc TAZVERIK tazemetostat hydrobromide TABLET;ORAL 211723-001 Jan 23, 2020 RX Yes Yes 10,245,269 ⤷  Try for Free METHOD OF TREATING RELAPSED OR REFRACTORY FOLLICULAR LYMPHOMA BY INHIBITING EZH2 ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,245,269

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2013245878 ⤷  Try for Free
Australia 2018200168 ⤷  Try for Free
Brazil 112014025508 ⤷  Try for Free
Canada 2870005 ⤷  Try for Free
China 104603130 ⤷  Try for Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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