Last Updated: July 27, 2026

Details for Patent: 10,183,006


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Which drugs does patent 10,183,006 protect, and when does it expire?

Patent 10,183,006 protects RAVICTI and is included in one NDA.

This patent has thirty-four patent family members in twenty-four countries.

Summary for Patent: 10,183,006
Title:Methods of therapeutic monitoring of nitrogen scavenging drugs
Abstract:The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
Inventor(s):Bruce SCHARSCHMIDT, Masoud Mokhtarani
Assignee: Horizon Therapeutics US Holding LLC
Application Number:US15/980,376
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,183,006
Patent Claim Types:
see list of patent claims
Use; Delivery;

Drugs Protected by US Patent 10,183,006

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Horizon Therap Us RAVICTI glycerol phenylbutyrate LIQUID;ORAL 203284-001 Feb 1, 2013 AA RX Yes Yes 10,183,006 ⤷  Start Trial TREATMENT OF A UREA CYCLE DISORDER ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,183,006

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2012316750 ⤷  Start Trial
Australia 2017251691 ⤷  Start Trial
Brazil 112014007357 ⤷  Start Trial
Canada 2850391 ⤷  Start Trial
Chile 2014000783 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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