Details for Patent: 10,125,171

Which drugs does patent 10,125,171 protect, and when does it expire?

Patent 10,125,171 protects SYFOVRE and EMPAVELI and is included in two NDAs.

This patent has thirty patent family members in twelve countries.

Summary for Patent: 10,125,171

Title:	Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof
Abstract:	In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs. In some aspects, the invention further provides methods of using cell-reactive compstatin analogs, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides long-acting compstatin analogs and compositions comprising long-acting compstatin analogs. In some aspects, the invention further provides methods of using long-acting compstatin analogs, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides targeted compstatin analogs and compositions comprising targeted compstatin analogs. In some aspects, the invention further provides methods of using targeted compstatin analogs, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ.
Inventor(s):	Francois; Cedric (Louisville, KY), Deschatelets; Pascal (Louisville, KY)
Assignee:	Apellis Pharmaceuticals, Inc. (Crestwood, KY)
Application Number:	14/116,591
Patent Claim Types: see list of patent claims	Compound;

Drugs Protected by US Patent 10,125,171

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Apellis Pharms	SYFOVRE	pegcetacoplan	SOLUTION;INTRAVITREAL	217171-001	Feb 17, 2023		RX	Yes	Yes				Y
Apellis Pharms	EMPAVELI	pegcetacoplan	SOLUTION;SUBCUTANEOUS	215014-001	May 14, 2021		RX	Yes	Yes				Y

Foreign Priority and PCT Information for Patent: 10,125,171

PCT Information
PCT Filed	May 11, 2012	PCT Application Number:	PCT/US2012/037648
PCT Publication Date:	November 15, 2012	PCT Publication Number:	WO2012/155107

International Family Members for US Patent 10,125,171

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2012253294
Australia	2017245334
Australia	2019226186
Brazil	112013028816