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Last Updated: April 24, 2024

Details for Patent: 10,119,143


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Which drugs does patent 10,119,143 protect, and when does it expire?

Patent 10,119,143 protects GIVLAARI and is included in one NDA.

This patent has sixty-eight patent family members in thirty-six countries.

Summary for Patent: 10,119,143
Title:Compositions and methods for inhibiting expression of the ALAS1 gene
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1.
Inventor(s): Bettencourt; Brian (Groton, MA), Fitzgerald; Kevin (Brookline, MA), Querbes; William (Cambridge, MA), Desnick; Robert J. (New York, NY), Yasuda; Makiko (New York, NY)
Assignee: ALNYLAM PHARMACEUTICALS, INC. (Cambridge, MA) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY)
Application Number:15/027,176
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 10,119,143

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc GIVLAARI givosiran sodium SOLUTION;SUBCUTANEOUS 212194-001 Nov 20, 2019 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y TREATMENT OF ACUTE HEPATIC PORPHYRIA ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,119,143

PCT Information
PCT FiledOctober 03, 2014PCT Application Number:PCT/US2014/059160
PCT Publication Date:April 09, 2015PCT Publication Number: WO2015/051318

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