Last Updated: October 27, 2026

Details for Patent: 10,059,714


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Which drugs does patent 10,059,714 protect, and when does it expire?

Patent 10,059,714 protects TRUQAP and is included in one NDA.

This patent has fifty-five patent family members in forty-four countries.

Summary for Patent: 10,059,714
Title:Protein kinase B inhibitors
Abstract:The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).
Inventor(s):Paul David Johnson, Andrew Leach, Richard William Arthur Luke, Zbigniew Stanley Matusiak, Jeffrey James Morris
Assignee: AstraZeneca AB
Application Number:US15/351,481
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,059,714
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 10,059,714

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astrazeneca TRUQAP capivasertib TABLET;ORAL 218197-001 Nov 16, 2023 RX Yes No 10,059,714 ⤷  Start Trial Y Y ⤷  Start Trial
Astrazeneca TRUQAP capivasertib TABLET;ORAL 218197-002 Nov 16, 2023 RX Yes Yes 10,059,714 ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,059,714

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2201012 ⤷  Start Trial C02201012/01 Switzerland ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial 301299 Netherlands ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial PA2024532 Lithuania ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial CA 2024 00047 Denmark ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial 2024C/543 Belgium ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial CR 2024 00047 Denmark ⤷  Start Trial
European Patent Office 2201012 ⤷  Start Trial 122024000062 Germany ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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