Details for Patent: 10,035,822

Which drugs does patent 10,035,822 protect, and when does it expire?

Patent 10,035,822 protects SYFOVRE and EMPAVELI and is included in two NDAs.

This patent has forty-six patent family members in twenty-three countries.

Summary for Patent: 10,035,822

Title:	Cell-reactive, long-acting, or targeted compstatin analogs and related compositions and methods
Abstract:	Long-acting compstatin analogs comprising a clearance-reducing moiety attached to two compstatin analog moieties, each compstatin analog moiety comprising a cyclic peptide extended by a lysine residue or a sequence comprising a lysine residue at the N-terminus, C-terminus, or both, wherein the lysine residue is separated from the cyclic portion of the peptide by a rigid or flexible spacer comprising an oligo(ethylene glycol) moiety, the clearance reducing moiety comprises a linear polymer, wherein each end of the linear polymer is linked to one of the compstatin analog moieties by way of a carbamate, wherein (i) the spacer comprises --(CH2).sub.m-- and --(O--CH2-CH2--).sub.n joined covalently, wherein m is between 1 and 10 and n is between 1 and 10; and/or (ii) the spacer comprises 8-amino-3,6-dioxaoctanoic acid (AEEAc) or 11-amino-3,6,9-trioxaundecanoic acid.
Inventor(s):	Francois; Cedric (Louisville, KY), Deschatelets; Pascal (Louisville, KY)
Assignee:	Apellis Pharmaceuticals, Inc. (Crestwood, KY)
Application Number:	14/443,143
Patent Claim Types: see list of patent claims	Compound;

Drugs Protected by US Patent 10,035,822

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Apellis Pharms	SYFOVRE	pegcetacoplan	SOLUTION;INTRAVITREAL	217171-001	Feb 17, 2023		RX	Yes	Yes				Y
Apellis Pharms	EMPAVELI	pegcetacoplan	SOLUTION;SUBCUTANEOUS	215014-001	May 14, 2021		RX	Yes	Yes				Y

Foreign Priority and PCT Information for Patent: 10,035,822

PCT Information
PCT Filed	November 15, 2013	PCT Application Number:	PCT/US2013/070417
PCT Publication Date:	May 22, 2014	PCT Publication Number:	WO2014/078731

International Family Members for US Patent 10,035,822

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2013344462
Australia	2018247243
Australia	2020260435
Australia	2023200929
Brazil	112015011244