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Last Updated: May 18, 2025

Details for Patent: 10,028,944


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Summary for Patent: 10,028,944
Title:Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
Abstract: Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.
Inventor(s): Weiner; David M. (San Diego, CA), Davis; Robert E. (San Diego, CA), Brann; Mark R. (Rye, NH), Andersson; Carl-Magnus A. (Hjarup, SE), Uldam; Allan K. (Vaerloese, DK)
Assignee: ACADIA PHARMACEUTICALS INC. (San Diego, CA)
Application Number:15/397,582
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,028,944
Patent Claim Types:
see list of patent claims
Use; Dosage form;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 10,028,944: A Detailed Analysis

Introduction

Patents are a cornerstone of innovation, providing exclusive rights to inventors and companies for their intellectual property. The scope and claims of a patent are crucial in defining the boundaries of this exclusivity. This article will delve into the specifics of United States Patent 10,028,944, analyzing its scope, claims, and the broader patent landscape.

What is United States Patent 10,028,944?

United States Patent 10,028,944 is a patent granted for a specific invention, but to provide a detailed analysis, we need to understand the general context in which such patents are issued and the key components that define them.

Patent Scope: An Overview

Patent scope refers to the breadth and depth of protection granted by a patent. It is a critical aspect in determining the validity and enforceability of a patent. Two simple metrics often used to measure patent scope are independent claim length and independent claim count[3].

Independent Claim Length

Independent claims are those that stand alone and do not depend on other claims. The length of these claims can indicate the complexity and specificity of the invention. Generally, shorter independent claims suggest narrower and more focused protection, while longer claims may indicate broader protection but also increased complexity and potential ambiguity[3].

Independent Claim Count

The number of independent claims also provides insight into the scope of the patent. More independent claims can indicate a broader scope, as each claim may cover different aspects of the invention. However, this can also lead to increased litigation risks due to the potential for overlapping or overly broad claims[3].

Claims Construction

Claims construction is a critical process in patent litigation where the court interprets the meaning of the claims in a patent. This process is essential in determining the scope of the patent and can significantly impact the outcome of patent disputes. For example, in the case of Acadia Pharmaceuticals' NUPLAZID formulation patent, the Delaware District Court's claims construction order was a significant milestone in establishing the patent's validity and scope[1].

Patent Claims Data

The United States Patent and Trademark Office (USPTO) provides extensive datasets on patent claims, which can be used to analyze trends and metrics related to patent scope. These datasets include detailed information on claims from US patents granted between 1976 and 2014 and US patent applications published between 2001 and 2014. The data includes individually-parsed claims, claim-level statistics, and document-level statistics, offering a comprehensive view of patent claims and their scope[2][5].

Analyzing the Specifics of United States Patent 10,028,944

To analyze the specifics of this patent, one would typically review the patent document itself, which includes the abstract, description, claims, and references cited.

Abstract and Description

The abstract provides a brief summary of the invention, while the description section details the invention's background, summary, and detailed description. These sections help in understanding the context and purpose of the invention.

Claims

The claims section is the most critical part of the patent document, as it defines the legal boundaries of the invention. Here, you would look at the independent and dependent claims to understand the scope of protection.

References Cited

The references cited section lists prior art and other relevant documents that were considered during the patent examination process. This helps in understanding the novelty and non-obviousness of the invention.

Example: Analyzing NUPLAZID Patents

While the specific details of United States Patent 10,028,944 are not provided here, we can use the example of Acadia Pharmaceuticals' NUPLAZID patents to illustrate the analysis process. NUPLAZID, a drug for treating psychosis in Parkinson's disease, has multiple patents with different expiration dates and types of protection (e.g., formulation, method of use, composition of matter)[1].

Impact on Innovation and Litigation

The scope and claims of a patent can significantly impact innovation and litigation. Narrower claims may reduce litigation risks but could also limit the inventor's protection. Broader claims, while offering more comprehensive protection, can increase the risk of litigation and challenges to the patent's validity[3].

Industry Expert Insights

Industry experts often emphasize the importance of carefully crafting patent claims to balance protection with the risk of litigation. For instance, Steve Davis, President and CEO of Acadia Pharmaceuticals, highlighted the importance of establishing claims construction in patent litigation, underscoring the strength of their patent estate[1].

Statistics and Trends

Analyzing large-scale datasets on patent claims can reveal trends and patterns. For example, research has shown that narrower claims at publication are associated with a higher probability of grant and a shorter examination process than broader claims[3].

Conclusion

Understanding the scope and claims of a patent is essential for inventors, companies, and legal professionals. By analyzing the independent claim length, independent claim count, and the overall claims construction, one can gain insights into the patent's validity and enforceability.

Key Takeaways

  • Patent Scope Metrics: Independent claim length and count are key metrics in measuring patent scope.
  • Claims Construction: Court interpretations of claims are crucial in determining patent scope and validity.
  • Patent Claims Data: USPTO datasets provide valuable information on patent claims and trends.
  • Impact on Innovation: The scope of a patent can influence innovation and litigation risks.
  • Industry Insights: Carefully crafting patent claims is vital for balancing protection and litigation risks.

FAQs

What is the importance of independent claims in a patent?

Independent claims are crucial as they stand alone and define the core protection of the invention. Their length and count can indicate the complexity and breadth of the patent.

How does claims construction impact patent litigation?

Claims construction by the court determines the meaning and scope of the patent claims, which can significantly influence the outcome of patent disputes.

What metrics are used to measure patent scope?

Common metrics include independent claim length and independent claim count, which provide insights into the complexity and breadth of the patent protection.

Why is it important to analyze patent claims data?

Analyzing patent claims data helps in understanding trends, identifying potential risks, and optimizing the drafting of patent claims to balance protection and litigation risks.

How do broader claims affect patent litigation?

Broader claims can increase the risk of litigation and challenges to the patent's validity, although they may offer more comprehensive protection.

Sources

  1. Acadia Pharmaceuticals: "Delaware District Court Rules in Favor of Acadia on Formulation Patent Construction Markman Claims Regarding NUPLAZID."
  2. USPTO: "Patent Claims Research Dataset."
  3. SSRN: "Patent Claims and Patent Scope" by Marco, Alan C., Sarnoff, Joshua D., and deGrazia, Charles.
  4. Google Patents: "Patent No. US10646480."
  5. USPTO: "Patent and patent application Claims data (Stata (.dta) and MS Excel (.csv))."

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Drugs Protected by US Patent 10,028,944

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,028,944

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 407117 ⤷  Try for Free
Austria 512136 ⤷  Try for Free
Australia 2004206886 ⤷  Try for Free
Brazil PI0406591 ⤷  Try for Free
Canada 2512639 ⤷  Try for Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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