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Harvard Business School
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Generated: December 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 10,004,746

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Which drugs does patent 10,004,746 protect, and when does it expire?

Patent 10,004,746 protects IMBRUVICA and is included in two NDAs.

This patent has thirty patent family members in seventeen countries.

Summary for Patent: 10,004,746
Title:Use of inhibitors of Bruton's tyrosine kinase (Btk)
Abstract: Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
Inventor(s): Buggy; Joseph J. (Mountain View, CA), Elias; Laurence (Berkeley, CA), Fyfe; Gwen (San Francisco, CA), Hedrick; Eric (Summit, NJ), Loury; David J. (Incline Village, NV), Mody; Tarak D. (Sunnyvale, CA)
Assignee: Pharmacyclics LLC (Sunnyvale, CA)
Application Number:15/659,803
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,004,746
Patent Claim Types:
see list of patent claims

Drugs Protected by US Patent 10,004,746

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-002 Dec 20, 2017 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial TREATMENT OF SMALL LYMPHOCYTIC LYMPHOMA WITH 17P DELETION ➤ Try a Free Trial
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-002 Dec 20, 2017 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P DELETION ➤ Try a Free Trial
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-002 Dec 20, 2017 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Teva
Colorcon
Baxter
QuintilesIMS
US Army
Queensland Health
Merck
Fish and Richardson

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