DrugPatentWatch Database Preview
Details for Patent: 10,004,746
Which drugs does patent 10,004,746 protect, and when does it expire?
Patent 10,004,746 protects IMBRUVICA and is included in two NDAs.
This patent has thirty patent family members in seventeen countries.
Summary for Patent: 10,004,746
| Title: | Use of inhibitors of Bruton's tyrosine kinase (Btk) |
| Abstract: | Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. |
| Inventor(s): | Buggy; Joseph J. (Mountain View, CA), Elias; Laurence (Berkeley, CA), Fyfe; Gwen (San Francisco, CA), Hedrick; Eric (Summit, NJ), Loury; David J. (Incline Village, NV), Mody; Tarak D. (Sunnyvale, CA) |
| Assignee: | Pharmacyclics LLC (Sunnyvale, CA) |
| Application Number: | 15/659,803 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 10,004,746 |
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Patent Claim Types: see list of patent claims |
Drugs Protected by US Patent 10,004,746
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pharmacyclics Inc | IMBRUVICA | ibrutinib | CAPSULE;ORAL | 205552-002 | Dec 20, 2017 | RX | Yes | No | ➤ Try a Free Trial | ➤ Try a Free Trial | TREATMENT OF SMALL LYMPHOCYTIC LYMPHOMA WITH 17P DELETION | ➤ Try a Free Trial | ||||
| Pharmacyclics Inc | IMBRUVICA | ibrutinib | CAPSULE;ORAL | 205552-002 | Dec 20, 2017 | RX | Yes | No | ➤ Try a Free Trial | ➤ Try a Free Trial | TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P DELETION | ➤ Try a Free Trial | ||||
| Pharmacyclics Inc | IMBRUVICA | ibrutinib | CAPSULE;ORAL | 205552-002 | Dec 20, 2017 | RX | Yes | No | ➤ Try a Free Trial | ➤ Try a Free Trial | TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA | ➤ Try a Free Trial | ||||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
International Family Members for US Patent 10,004,746
| Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2011261185 | ➤ Try a Free Trial | |||
| Australia | 2015275321 | ➤ Try a Free Trial | |||
| Australia | 2018204179 | ➤ Try a Free Trial | |||
| Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
