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Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Merck
UBS
Federal Trade Commission
Citi
Express Scripts
McKesson
Farmers Insurance
Teva

Generated: June 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 9,687,478

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Title:Quinuclidine derivatives and medicinal compositions containing the same
Abstract: Provided is an aerosol container comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane wherein an anion X.sup.- is associated with the positive charge of the nitrogen atom and wherein X.sup.- is a pharmaceutically acceptable anion of a mono- or polyvalent acid.
Inventor(s): Fernandez Forner; Maria Dolors (Barcelona, ES), Prat Quinones; Maria (Barcelona, ES), Buil Albero; Maria Antonia (Barcelona, ES)
Assignee: ALMIRALL, S.A. (Barcelona, ES)
Filing Date:Apr 09, 2016
Application Number:15/095,036
Claims:1. An aerosol container comprising a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane wherein an anion X.sup.- is associated with the positive charge of the nitrogen atom and wherein X.sup.- is a pharmaceutically acceptable anion of a mono- or polyvalent acid.

2. The aerosol container of claim 1, wherein the powder inhalant further comprises a pharmaceutically acceptable carrier or diluent.

3. The aerosol container of claim 2, wherein the pharmaceutically acceptable carrier or diluent of the powder inhalant is lactose.

4. The aerosol container of claim 1, wherein the powder inhalant further comprises a .beta..sub.2 agonist.

5. The aerosol container of claim 4, wherein the powder inhalant further comprises a steroid or a phosphodiesterase IV inhibitor.

6. The aerosol container of claim 1, wherein the powder inhalant further comprises a steroid.

7. The aerosol container of claim 6, wherein the powder inhalant further comprises a phosphodiesterase IV inhibitor.

8. The aerosol container of claim 1, wherein the powder inhalant further comprises a phosphodiesterase IV inhibitor.

9. A method for treating chronic obstructive pulmonary disease, chronic bronchitis, bronchial hyperreactivity, asthma, or rhinitis which method comprises use of an aerosol container of claim 1 to administer to a human or animal patient in need of such treatment an effective amount of the powder inhalant of claim 1.

10. The method of claim 9 further comprising administering an effective amount of a .beta..sub.2 agonist.

11. The method of claim 10 further comprising administering an effective amount of a steroid or a phosphodiesterase IV inhibitor.

12. The method of claim 9 further comprising administering an effective amount of a steroid.

13. The method of claim 12 further comprising administering an effective amount of a phosphodiesterase IV inhibitor.

14. The method of claim 9 further comprising administering an effective amount of a phosphodiesterase IV inhibitor.

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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Moodys
Argus Health
Cipla
US Army
Citi
Johnson and Johnson
AstraZeneca
Dow

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