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Generated: September 24, 2018

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Details for Patent: 9,642,797

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Title:Sublingual fentanyl spray and methods of use to treat pain
Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
Inventor(s): Kottayil; S. George (Long Grove, IL), Goskonda; Venkat R. (Phoenix, AZ), Zhu; Zhongyuan (Vernon Hills, IL), Kattookaran; Linet (Mount Prospect, IL), Parikh; Neha (Chicago, IL)
Assignee: INSYS DEVELOPMENT COMPANY, INC. (Chandler, AZ)
Filing Date:Feb 12, 2016
Application Number:15/042,999
Claims:1. A sublingual formulation comprising from about 0.1% to about 0.9% by weight fentanyl, a free base or a pharmaceutically acceptable salt thereof, or a derivative thereof, from about 20% to about 60% by weight ethanol and from about 4% to about 6% by weight propylene glycol.

2. The composition of claim 1, wherein ethanol is at a concentration from about 50% to about 60%.

3. A method of treating pain comprising administering an effective amount of the formulation of claim 1.

4. The method of claim 3, wherein the pain is breakthrough pain.

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