Details for Patent: 9,642,797

Title:	Sublingual fentanyl spray and methods of use to treat pain
Abstract:	The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
Inventor(s):	Kottayil; S. George (Long Grove, IL), Goskonda; Venkat R. (Phoenix, AZ), Zhu; Zhongyuan (Vernon Hills, IL), Kattookaran; Linet (Mount Prospect, IL), Parikh; Neha (Chicago, IL)
Assignee:	INSYS DEVELOPMENT COMPANY, INC. (Chandler, AZ)
Filing Date:	Feb 12, 2016
Application Number:	15/042,999
Claims:	1. A sublingual formulation comprising from about 0.1% to about 0.9% by weight fentanyl, a free base or a pharmaceutically acceptable salt thereof, or a derivative thereof, from about 20% to about 60% by weight ethanol and from about 4% to about 6% by weight propylene glycol. 2. The composition of claim 1, wherein ethanol is at a concentration from about 50% to about 60%. 3. A method of treating pain comprising administering an effective amount of the formulation of claim 1. 4. The method of claim 3, wherein the pain is breakthrough pain.