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Last Updated: March 29, 2024

Details for Patent: 9,517,236


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Title:Controlled release hydrocodone formulations
Abstract: A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.
Inventor(s): Oshlack; Benjamin (Boca Raton, FL), Huang; Hua-Pin (Englewood Cliffs, NJ), Masselink; John K. (Old Tappan, NJ), Tonelli; Alfred (Congers, NY)
Assignee: Purdue Pharma L.P. (Stamford, CT)
Filing Date:Feb 09, 2016
Application Number:15/019,695
Claims:1. cited by applicant .
Hansch C et al.,"Comprehensive Medicinal Chemistry, vol. 5 Biopharmaceutics," Rational Design, Mechanistic Study and Therapeutic Application of Chemical Compounds, Oxford, Pergamon Press, GB, vol. 5, 1990, pp. 251-278, XP008054499. cited by applicant .
Ratain M J et al., "Population Pharmacodynamic Study of Amonafide: A Cancer and Leukemia Group B Study," Journal of Clinical Oncology, Grune and Stratton, New York, NY, US, vol. 13, No. 3, Mar. 1995, pp. 741-747, XP008044974 ISSN: 0732-183X. cited by applicant .
Database Medline [Online] US National Library of Medicine (NLM), Bethesda, MD, US; Aug. 1994, Yasuhara H: "Ethnic factors in evaluation of drug efficacy and safety," XP002350633 Database accession No. NLM7927070. cited by applicant .
Setiabidu R et al., "Dapsone N-Acetylation, Metoprolol, Alpha-Hydroxylation, and S-Mephenytoin 4-Hydroxylation Polymorphisms in an Indonesian Population: A Cocktail and Extended Phenotyping Assessment Trail," Clinical Pharmacology & Therapeutics, Mosby--Year Book, St Louis, MO, US, vol. 56, No. 2, Aug. 1994, pp. 142-153, XP008044975 ISSN: 0009-9236. cited by applicant .
"Helsinki Declaration" Online Ethics Center, [Online] Apr. 5, 2005, XP002350634 Retrieved from the Internet: URL:http://onlineethics.org/reseth/helsink i.html> retrieved on Oct. 25, 2005. cited by applicant .
Castensen et al., "USP Dissolution IV:Comparison of Methods," J. Pham. Sci 1978, 67(9), pp. 1303-1307. cited by applicant .
Encarta World English Dictionary [North American Edition] 2006 Microsoft Incorporation "Matrix", p. 1, definition 2, http://encarta.msn.com/encnet/features/dictionary/DictionaryResults.aspx?- - refid=861678516 retrieved on Apr. 30, 2006. cited by applicant .
Wiktionary, "dispersed," p. 1, http://en.wiktionary.org/wiki/disperse retrived on Apr. 30, 2006. cited by applicant .
Abraham Sunshine et al., "Analgesic Oral Efficacy of Tramadol Hydrochloride in Postoperative Pain," Clin. Pharmacol. Ther., vol. 51, Jun. 1992, pp. 740-746. cited by applicant .
E.Beubler, "Medikamentose Schmerztherapie: Kriterien, Moglichkeiten, Risken," Therapiewoche Osterreich, 7,2 (1992), pp. 1-15, English translation. cited by applicant .
Gourlay, et al., "Influence of a High-Fat Metal on the Absorption of Morphine From Oral Solutions," Clin. Pharmacol. Ther., vol. 46, Oct. 1989, pp. 463-468. cited by applicant .
Geoffrey K. Gourlay, et al.,"The Reproducibility of Bioavailability of Oral Morphine from Solution Under Fed and Fasted Conditions," Journal of Pain and Symtoms Management, vol. 6., No. 7, Oct. 1991, pp. 431-436. cited by applicant .
Robert F. Kaiko, et al., "Controlled-Release Morphine Bioavailability (MS Contin Tablets) in the Presence and Absence of Food," The Hospice Journal, vol. 6(4) 1990, pp. 17-30. cited by applicant .
Yokokawa N., et al., "Relationship between plasma concentration of morphine and analgesic effectiveness," Postgrad Med J. (1991) 67 (Suppl. 2) pp. S50-S54. cited by applicant .
Physicians Desk Reference 1994, 48th Edition, pp. 1821-1824. cited by applicant .
D.L. Munday, et al., "Changes in Drug Release Rate 2. Effect of Temperature and Relative Humidity on Polymeric Film Coatings," 5th Cong. Int. Tech. Pharm., 1989, vol. 2, pp. 55-60. cited by applicant .
A Protocol for a clinical study entitled "A Randomized, Double-Blind, Parallel-Group Study comparing the Efficacy and Safety of Kapanol.RTM. to MS Contin.RTM., in the Management of Patients with Moderate to Severe Cancer Pain" ("the Protocol"). The date of the Protocol is indicated as Feb. 10, 1992 and it bears COD No. 14556. The sponsor of the study is indicated to be Faulding Pharmaceuticals, an Australian company. cited by applicant .
Certain Patients Diary Cards, Drug Disposition Records, Case Reports Forms and listing which apparently correlates patient randomization number with the treatment of dosing regimen assigned to each patient, 2003. cited by applicant .
Patient consent forms, apparently for four study participants, 2003. cited by applicant .
Investigator agreements between the study organizers and certain of the principal investigators, 2003. cited by applicant .
Abstracts from the Twelfth Annual Congress of the Oncology Nursing Society, May 1987, In Clinical Nursing Forum Supplement vol. 14 (2), p. 112, 1987. cited by applicant .
J. Lapin et al., "Cancer Pain Management with a Controlled Release Oral Morphine Preparation," Pain and Symptom Manag., vol. 4 (3), pp. 146-151,1989. cited by applicant .
J. Lapin et al., "Guidelines for Use of Controlled Release Oral Morphine in Cancer Pain Management," Cancer Nursing, vol. 12 (4), pp. 202-208, (1989). cited by applicant .
R.K.. Kaiko, "The Pre- and Postoperative Use of Controlled-Release Morphine (MS Contin Tablets): A Review of the Published Literature," Medical Department, The Pudue Frederick Company, Royal Society of Medical Services, International Congress, Symposium Services, No. 149, pp. 147-160 (1989). cited by applicant .
H.F. Stowey et al., "Effect of Premedication with Controlled-Release Oral Morphine on Postoperative Pain," Anesthesia, 1985, vol. 40, pp. 438-440. cited by applicant .
MS Contin--Frequency of Daily Dosing, Jan.-Nov. 1990. cited by applicant .
R.K. Portenoy, et al., "A Randomized, Double-Blind, Double-Dummy, Crossover Study Comparing the Pharmacolinetics and Pharmacodynamics of Kapanol.RTM. Capsules Given Every 24 hours and Every 12 hours with MS Contin.RTM. Tablets Given Every 12 Hours in the Management of Patients with Moderate to Severe Chronic Pain," Memorial Hospital IRB Protocol pp. 379-381, 1993. cited by applicant .
7th World Congress on Pain, Abstracts 997-1001, Aug. 26, 1993. cited by applicant .
Advertisement: Raxanol SR., 1988 Roxane Labs, Inc. cited by applicant .
T. Hunt and R. Kaiko, "Comparison of the Pharmacokinetic Profiles of Two Oral Controlled-Release Morphine Formulation in Healthy Young Adults," Clin. Thera., vol. 13, No. 4, pp. 482-488, 1991. cited by applicant .
S. Bloomfield, et al., "Analgesic Efficacy and Potency of Two Oral Controlled-Release Morphine Preparations Clin. Pharmacol," Ther., vol. 53, No. 4, pp. 469-478, 1993. cited by applicant .
Advertisement: MS Contin 1986, 1987 The Purdue Frederick Company. cited by applicant .
Sustained Release Medications, Noyes Data Corp., pp. 3,4, 10-15, 96-99, 335-337 (1980). cited by applicant .
Flanders, P., et al., "The Control of Drug Release From Conventional Melt Granulation Matrices," Drug Development and Industrial Pharmacy, vol. 13, No. 6, pp. 1001-1022 (1987). cited by applicant .
McTaggart, Celia M., et al., "The evaluation of formulation and processing conditions of a melt granulation process," International Journal of Pharmaceutics, vol. 19, pp. 139-148 (1984). cited by applicant .
Schaefer, T., et al., "Melt granulation in a laboratory scale high shear mixer," Drug Development and Industrial Pharmacy, vol. 16, No. 8, pp. 1249-1277 (1990). cited by applicant .
Thomsen, L. Juul, et al., "Prolonged Release Matrix Pellets Prepared by Melt Pelletization I. Process Variables," Drug Development and Industrial Pharmacy, vol. 19, No. 15, pp. 1867-1887 (1993). cited by applicant .
Thomsen, L. Juul, "Prolonged Release Matrix Pellets prepared by Melt Pelletization II. Hydrophobic Substances as Meltable Binders," vol. 20, No. 77, pp. 1179-1197 (1994). cited by applicant .
Thomsen, L. Juul, "Utilizing melt pelletization technique for the preparation of prolonged release products," Pelletization, (material elaborated by assistant prof. Lars Jull Thomsen, Department of Pharmaceutics, Royal Danish School of Pharmacy of the DIE course "Pelletization Technology," Nov. 1992, 106 pages plus 3 appendices. cited by applicant .
Thomsen, L. Juul, "Prolonged Release Matrix Pellets Prepared by Melt Pelletization. Part IV: Drug Particles Size, and Binder Composition," Pharmaceutical Technology Europa, pp. 19-24 (Oct. 1994). cited by applicant .
Maccarrone C. et al.,"Single Dose Pharmacokinetics of Kapanol.TM. a New Oral Sustained-Release Morphine Formulation," Clinical Drug Investigation 1994:7 (5) 262-274. cited by applicant .
West R. J., et al., "Single dose pharmacokinetics of a new oral sustained release morphine formulation, Kapanol.TM. capsules," (Abstract 997) International Association for the Study of Pain, 7th World Congress on Pain. Paris, Aug. 22-27, 1993 (Data on file, Glaxo Australia, F.H. Faulding). cited by applicant .
Gourlay GK, et al., "A comparison of Kapanol.TM. (A new sustained release morphine formulation), MST Contius.RTM. and morphine solution in cancer patients: pharmacokinetics aspects," (Abstract 998) International Association for the Study of Pain, 7th World Congress on Pain Paris, Aug. 22-27, 1993 (Data on file, Glaxo Australia, F.H. Faulding). cited by applicant .
Cherry DA, et al., "A comparison of Kapanol.TM. (A new sustained release morphine formulation), MST Continus.TM. and morphine solution in cancer patients: Morphine metabolite profiles and renal function," (Abstract 999) International Association for the Study of Pain, 7th World Congress on Pain, Paris Aug. 22-27, 1993 (Data on file, Glaxo Australia, F.H. Faulding). cited by applicant .
Plummer JL, et al., "A comparison of Kapanol.TM. (a new sustained release morphine formulation) MST Continus.TM. and mophine solution in cancer patients: pharmcodynamic aspects," (Abstract 1000) International Association for the Study of Pain, 7th World Congress on Pain, Paris, Aug. 22-27, 1993 (Data on file, Glaxo Australia, F.H. Faulding). cited by applicant .
Toner G, Cramond T, Bishop, et al., "Randomized double blind, phase III crossover study of a new sustained-release oral mophine fomulation, Kapanol.TM. capsules," (Abstract 1001) International Association for the Study on Pain, Paris, Aug. 22-27, 1993 (Data on file, Glaxo Australia, F.H. Faulding). cited by applicant .
Cherry DA, et al., "Once a Day (i.e. 24 Hourly) Kapanol.TM., A New Sustained Release Morphine Formulation, in the Treatment of Cancer Pain: Morphine Metabolite Profiles," European Journal of Cancer; Part A General Topics 1995; 31 (S5) Suppl:S184 Abs 884, European Conference on Clinical Oncology and Cancer Nursing, Paris, Oct. 29-Nov. 2, 1995. cited by applicant .
Gourlay, et al., "Once a Day (i.e. 24 Hourly) Kapanol.TM., A New Sustained Release Morphine Formulation, In the Treatment of Cancer Pain: Pharmacokinetic Aspects," European Journal of Cancer; Part A General Topics 1995:31 (S5) Suppl: S187 Abs 897, European Conference on Clinical Oncology and Cancer Nursing, Paris, Oct. 29-Nov. 2, 1995. cited by applicant .
Broomhead, et al., "Kadian.TM./Kapanol.TM.--A Once Daily Mophine Formulation," European Journal of Cancer; Part A General Topics 1995:31 (S5) Suppl: S182 Abs 873, European Conference on Clinical Oncloiogy and Cancer Nursing, Paris, Oct. 29-Nov. 2, 1995. cited by applicant .
Gourlay et al., "Proceedings of the 7th World Congress on Pain; A comparison of Kapanol (a New Sustained-Release Morphine Formulation), MST Continus, and Morphine Solution in Cancer Patients," Pharmacolinetic Aspects of Morphine and Morphine Metabolites Progress in Pain Research and Management vol. 2 pp. 631-643, 1993. cited by applicant .
MS Contin--Frequency of Daily Dosing (NDTI)--Jun. 1991-May 1992. cited by applicant .
Kaiko R.F., "Clinical Protocol and Role of Controlled Release Morphine in the Surgical Patient," Anesthesiology and Pain Management 1991 pp. 193-212. cited by applicant .
Kaiko et al., "A Single-Dose Study of the Effect of Food Ingestion and Timing of Dose Administration on the Pharmacokinetic Profile of 30-mg Sustained-Release Morphine Sulfate Tablets," Current Terapeutic Research, vol. 47, No. 5, May 1990, pp. 869-878. cited by applicant .
European Search Report issued in connection with European Application No. 10177503.8-2123 on Sep. 11, 2010. cited by applicant .
"The Merck Manual," Merck and Co., p. 4711 (1989). cited by applicant .
Goodman and Gilman's, The Pharmacological Basis of Therapeutics, pp. 7-8 (1990). cited by applicant .
Encyclopedia of Controlled Drug Delivery, vol. 1, "In vitro-in vivo correlation," pp. 425-435 (1999). cited by applicant .
Encyclopedia of Controlled Drug Delivery, vol. 2, "Oral drug delivery, small intestine & colon," pp. 698-728 (1999). cited by applicant .
Guidance for Industry, "Extended Release Oral Dosage Forms: Development, Evaluation, and Application of In Vitro/ In vivo Correlation" (FDA, 1997). cited by applicant .
Office Action issued on May 24, 2011, in connection with European Application No. 10 179 087.1-2123. cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 01 992 565.0-2123. cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 10 177 508.8-2123. cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 10 179 086.3-2123. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 10180984.6. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 10181032.3. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 10177508.8. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 01992565.0. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 10179087.1. cited by applicant .
Summons to attend oral proceedings issued on Jun. 5, 2013, in connection with European Patent Application No. 10179086.3. cited by applicant .
Opinion Expressed by the Board of Appeal in the Summons to Oral Proceedings in Case EP02026247 ( May 24, 2011). cited by applicant .
FDA Response to a Citizen Petition, Docket No. FDA-2013-P-0703, Oct. 25, 2013. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Feb. 26, 2014. cited by applicant .
Claims pending in U.S. Appl. No. 12/982,386 on May 7, 2014. cited by applicant .
Claims pending in U.S. Appl. No. 14/094,968 on May 7, 2014. cited by applicant .
Claims pending in U.S. Appl. No. 13/833,263 on May 7, 2014. cited by applicant .
Zohydro ER Package Insert revised Oct. 2013. cited by applicant .
Zohydro ER Hydrocodone Bitartrate Extended-Release (HC-ER) Dec. 7, 2012. cited by applicant .
Advisory Committee Briefing Document, NDA 20-2880, Zohydro.TM. ER Hydrocodone Bitartrate Extended-Release Capsules, Anesthetic and Analgesic Drug Products Advisory Committee, Dec. 7, 2012. cited by applicant .
Approval Package for NDA 20-616/5-001 (Kadian.RTM.), 1997. cited by applicant .
Kadian.RTM. Prescribing Information 2006. cited by applicant .
MS Contin.RTM. Prescribing Information 2012. cited by applicant .
Oxycontin.RTM. Prescribing Information 2010. cited by applicant .
Trandemate ER.RTM. Prescribing Information 2005. cited by applicant .
Benziger, et al., "A Pharmacokinetic/Pharmacodynamic Study of Controlled-Release Oxycodone", 1997. cited by applicant .
Decision to refuse a European Patent application issued in connection with European patent application No. 01992565.0-1464 on Jun. 27, 2014. cited by applicant .
Decision to refuse a European Patent application issued in connection with European patent application No. 10 180 984.6-1464 on Jul. 9, 2014. cited by applicant .
The Merck Index, eleventh edition, pp. 757 and 1100 (1989). cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 10 180 945.7. cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 10 180 984.6. cited by applicant .
Office Action issued on Jul. 27, 2012, in connection with European Application No. 10 181 032.3. cited by applicant .
European Search Report issued on Nov. 9, 2010 in connection with European Application No. 10180945.7-2123. cited by applicant .
English Translation of the Office Action issued on Mar. 22, 2011 in connection with Japanese Patent Application No. 2006-3165067. cited by applicant .
M.H. Beers: "The Merck Index, 11.sup.th edition," 1989, Merck & Co. CP002606249. cited by applicant .
Merk Index, 13.sup.th edition, entry 4806: hydrocodone (2001). cited by applicant .
EPI Journal Feb. 2007, pp. 59-60; David Harrison; "Divisional Application a continuing problem" (2007). cited by applicant .
Document CA/PL 17/07; "Misuse of Divisional Applications," by the EPO President, addressed to the EPO Committee of Patent Law. Presented at the EPO Administrative Council, dated Oct. 5, 2007. cited by applicant .
Document CA/PL 3/08, presented by epi and other Professional Representatives, addressed to the EPO Commiffee of Patent Law. Presented at the EPO Administrative Council, dated Feb. 14, 2008. cited by applicant .
Summons to Attend Oral Proceedings issued in connection with European Patent Application No. 05019453.9 on Jul. 23, 2010. cited by applicant .
English translation of Officie Action issued by Japanese Patent Office in connection with corresponding Japanese Patent Application No. 2001-534353 on May 25, 2010. cited by applicant .
Office Action issued in connection with Japanese patent application No. 2013-168584 on Sep. 16, 2014. cited by applicant .
Claims Pending in U.S. Appl. No. 12/982,386 on Oct. 20, 2014. cited by applicant .
Claims Pending in U.S. Appl. No. 13/833,263 on Oct. 20, 2014. cited by applicant .
Claims Pending in U.S. Appl. No. 14/094,968 on Oct. 20, 2014. cited by applicant .
Claims Pending in U.S. Appl. No. 14/483,395 on Oct. 20, 2014. cited by applicant .
Office Actlon lssued ln connection with U.S. Appl. No. 14/483,395 on Oct. 9, 2014. cited by applicant .
Office Action issued in connection U.S. Appl. No. 14/094,968 on Oct. 3, 2014. cited by applicant .
Office Actlon issued in connection with U.S. Appl. No. 14/094,968 on Feb. 6, 2014. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Oct. 9, 2014. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Aug. 13, 2014. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Dec. 19, 2013. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Sep. 4, 2013. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Apr. 30, 2013. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Dec. 27, 2012. cited by applicant .
Office Action issued in connection with U.S. Appl. No. 12/982,386 on Nov. 5, 2012. cited by applicant .
Declaration of Benjamin Oshlack filed in U.S. Appl. No. 13/833,263 on Dec. 24, 2014. cited by applicant .
Claims pending in U.S. Appl. No. 13/833,263 on Jan. 5, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/094,968 on Jan. 5, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 12/982,386 on Jan. 5, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/483,395 on Jan. 13, 2015. cited by applicant .
An English translation of the Notice on Reexamination issued in connection with Chinese patent application No. 200810125922.X on Dec. 3, 2014. cited by applicant .
Claims pending in U.S. Appl. No. 14/635,198 on Mar. 10, 2015. cited by applicant .
Amendment after final action under 37 C.F.R. .sctn. 1.116 filed in connection with U.S. Appl. No. 11/372,857 on Mar. 2, 2015. cited by applicant .
Declaration under 37 C.F.R. .sctn. 1.132 by Gurvinder Singh Rekhi filed in connection with U.S. Appl. No. 11/372,857 on Mar. 6, 2015. cited by applicant .
Declaration of Interference issued in connection with U.S. Appl. Nos. 11/372,857; 13/833,263 and 14/094,968 on Apr. 8, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/635,198 on Mar. 30, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/672,894 on Mar. 30, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/673,447 on Mar. 30, 2015. cited by applicant .
Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate Release Solid Oral Dosage Forms Containing Certain Active Moieties/Active Ingredients Based on a Biopharmaceutics Classification System (Issued Jan. 1999, Posted Feb. 16, 1999). cited by applicant .
J. W. Barnhart, .et. al., Gas Chromatographic Determination of Hydrocodone in Serum, 130 J. Chromatography 243-49, Abstract (1977). cited by applicant .
Interference 106,022, Paper 6 Oshlack Notice of Related Proceedings, Apr. 22, 2015. cited by applicant .
Interference 106,022, Paper 12 John G. Devane Notice of Related Proceedings, Apr. 22, 2015. cited by applicant .
Interference 106,022, Paper 14 Redeclaration 37 C.F.R. 203(c), Apr. 23, 2015. cited by applicant .
Interference 106,022, Paper 18 Purdue Pharma Motion List, May 7, 2015. cited by applicant .
Interference 106,022, Paper 19 Recro Motion List, May 8, 2015. cited by applicant .
Interference 106,022, Paper 20 Recro Statement Concerning Other Proceedings, May 8, 2015. cited by applicant .
Interference 106,022, Paper 21 Order Authorizing Motions and Setting Times, May 19, 2015. cited by applicant .
Interference 106,022, Paper 22 Redeclaration 37 C.F.R. 41.203(c), May 19, 2015. cited by applicant .
Interference 106,022, Paper 25 Decision Miscellaneous Motion Bd R 121(a)(3), Jul. 2, 2015. cited by applicant .
Interference 106,022, Paper 148 Recro Motion 3, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 123 Recro Motion 1, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 140 Recro Motion 5, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 27 Recro Exhibit List, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 142 Purdue Pharma Exhibit List, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 143 Purdue Pharma Motion 1, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 144 Purdue Pharma Motion 2, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 145 Purdue Pharma Motion 4, Jul. 10, 2015. cited by applicant .
Interference 106,022, Paper 152 Order--Responsive Motion, Jul. 24, 2015. cited by applicant .
Interference 106,022, Paper 154 Purdue Motion 5, Jul. 31, 2015. cited by applicant .
Interference 106,022, Paper 163 Recro Motion 6, Jul. 31, 2015. cited by applicant .
Interference 106,022, Paper 159 Recro Updated Exhibit List, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2001, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2002, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2003, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2004, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2005, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2006, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2007, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2008, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2009, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2010, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2011; Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2012, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2013, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2014, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2015, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2016, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2017, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2018, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2021, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2022, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2023, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2025, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2026, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2027, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2028, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2029, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2030, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2041, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2064, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 2065, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2066, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2067, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2068, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2069, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2070, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 2071, Jul. 31, 2015. cited by applicant .
Interference 106,022, Exhibit 1001, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1002, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1003, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1004, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1005, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1006, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1007, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1008, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1009, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1010, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1011, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1012, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1013, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1014, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1015, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1016, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1017, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1019, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1020, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1021, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1022, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1023, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1024, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1025, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1026, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1027, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1028, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1029, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1030, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1041, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1042, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1043, Jul. 10, 2015. cited by applicant .
Interference 106,022, Exhibit 1044, Jul. 10, 2015. cited by applicant .
English translation of the Office Action issued in connection with Japanese Application No. 2014-182108 on Aug. 11, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/727,985 on Aug. 21, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/727,997 on Aug. 21, 2015. cited by applicant .
Claims pending in U.S. Appl. No. 14/728,023 on Aug. 21, 2015. cited by applicant .
Interference 106,022, Paper 243: Decision on Motions--37 C.F.R. .sctn. 41.127, Apr. 29, 2016. cited by applicant.

Primary Examiner: Sasan; Aradhana
Attorney, Agent or Firm: Davidson, Davidson & Kappel, LLC

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