Details for Patent: 9,145,389

Title:	Benzimidazole compound crystal
Abstract:	A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
Inventor(s):	Fujishima; Akira (Hyogo, JP), Aoki; Isao (Hyogo, JP)
Assignee:	Takeda Pharmaceutical Company Limited (Osaka, JP)
Filing Date:	Oct 07, 2014
Application Number:	14/508,651
Claims:	1. A solid amorphous compound of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or salt thereof, having an optical purity of at least 98.3%. 2. The solid amorphous compound of claim 1, which is (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole having an optical purity of at least 98.3%. 3. A crystalline compound of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or salt thereof, having an optical purity of at least 99.8%, produced by dissolving the solid amorphous compound or salt thereof of claim 1 in a solvent to form a solution and precipitating crystals from the solution. 4. A pharmaceutical composition comprising the crystalline compound of claim 3 and a pharmaceutically acceptable carrier.