Details for Patent: 9,056,100
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Title: | Quinuclidine derivatives and medicinal compositions containing the same |
Abstract: | Provided is a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane bromide and methods of using the same. |
Inventor(s): | Fernandez Forner; Maria Dolors (Barcelona, ES), Prat Quinones; Maria (Barcelona, ES), Buil Albero; Maria Antonia (Barcelona, ES) |
Assignee: | ALMIRALL, S.A. (Barcelona, ES) |
Filing Date: | Jun 20, 2014 |
Application Number: | 14/311,102 |
Claims: | 1. A powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane bromide. 2. The powder inhalant of claim 1 further comprising a pharmaceutically acceptable carrier or diluent. 3. The powder inhalant of claim 2 wherein the pharmaceutically acceptable carrier or diluent is lactose. 4. The powder inhalant of claim 1 further comprising a .beta..sub.2 agonist. 5. The powder inhalant of claim 4 further comprising a steroid or a phosphodiesterase IV inhibitor. 6. The powder inhalant of claim 1 further comprising a steroid. 7. The powder inhalant of claim 6 further comprising a phosphodiesterase IV inhibitor. 8. The powder inhalant of claim 1 further comprising a phosphodiesterase IV inhibitor. 9. A method for treating chronic obstructive pulmonary disease, chronic bronchitis, bronchial hyperreactivity, asthma, or rhinitis which method comprises administering to a human or animal patient in need of such treatment an effective amount of the powder inhalant of claim 1. 10. The method of claim 9 further comprising administering an effective amount of a .beta..sub.2 agonist. 11. The method of claim 10 further comprising administering an effective amount of a steroid or a phosphodiesterase IV inhibitor. 12. The method of claim 9 further comprising administering an effective amount of a steroid. 13. The method of claim 12 further comprising administering an effective amount of a phosphodiesterase IV inhibitor. 14. The method of claim 9 further comprising administering an effective amount of a phosphodiesterase IV inhibitor. |