.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 9,050,349

« Back to Dashboard

Details for Patent: 9,050,349

Title:Synthetic bile acid compositions and methods
Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
Inventor(s): Moriarty; Robert M. (Michiana Shores, IN), David; Nathaniel E. (Los Angeles, CA), Mahmood; Nadir Ahmeduddin (Calabasas, CA)
Assignee: KYTHERA BIOPHARMACEUTICALS, INC. (Westlake Village, CA)
Filing Date:Jun 10, 2013
Application Number:13/914,510
Claims:1. A syringe or syringe-loadable container comprising a composition comprising a deoxycholate salt and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt.

2. The syringe or syringe-loadable container of claim 1, wherein said deoxycholate salt is sodium deoxycholate.

3. The syringe or syringe-loadable container of claim 2, wherein said sodium deoxycholate is present at a concentration of about 0.5% (w/v), about 1% (w/v), about 2% (w/v), or about 5% (w/v) in said composition.

4. The syringe or syringe-loadable container of claim 1, wherein said pharmaceutically acceptable excipient is selected from the group consisting of: water, a buffer, benzyl alcohol, and combinations thereof.

5. The syringe or syringe-loadable container of claim 1, wherein said pharmaceutically acceptable excipients consist of a buffer and benzyl alcohol.

6. The syringe or syringe-loadable container of claim 1, wherein the deoxycholate has a .sup.14C content of less than 0.9 ppt.

7. A syringe or syringe-loadable container comprising an aqueous pharmaceutical composition comprising a deoxycholate salt and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt.

8. The syringe or syringe-loadable container of claim 7, wherein said deoxycholate salt is sodium deoxycholate.

9. The syringe or syringe-loadable container of claim 8, wherein said sodium deoxycholate is present at a concentration of about 0.5% (w/v), about 1% (w/v), about 2% (w/v), or about 5% (w/v) in said composition.

10. The syringe or syringe-loadable container of claim 7, wherein said pharmaceutically acceptable excipient is selected from the group consisting of: water, a buffer, benzyl alcohol, and combinations thereof.

11. The syringe or syringe-loadable container of claim 7, wherein said pharmaceutically acceptable excipients consist of a buffer and benzyl alcohol.

12. The syringe or syringe-loadable container of claim 7, wherein the deoxycholate has a .sup.14C content of less than 0.9 ppt.

13. A syringe or syringe-loadable container comprising an aqueous pharmaceutical composition comprising a deoxycholate salt, phosphatidyl choline and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt.

14. The syringe or syringe-loadable container of claim 13, wherein said deoxycholate salt is sodium deoxycholate.

15. The syringe or syringe-loadable container of claim 14, wherein said sodium deoxycholate is present at a concentration of about 0.5% (w/v), about 1% (w/v), about 2% (w/v), or about 5% (w/v) in said composition.

16. The syringe or syringe-loadable container of claim 13, wherein said pharmaceutically acceptable excipient is selected from the group consisting of: water, a buffer, benzyl alcohol, and combinations thereof.

17. The syringe or syringe-loadable container of claim 13, wherein said pharmaceutically acceptable excipients consist of a buffer and benzyl alcohol.

18. The syringe or syringe-loadable container of claim 13, wherein the deoxycholate has a .sup.14C content of less than 0.9 ppt.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc