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Generated: February 21, 2018

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Title:5-HT.sub.1A receptor subtype agonist
Abstract: The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT.sub.1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): ##STR00001## wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
Inventor(s): Jordan; Shaun (Frederick, MD), Kikuchi; Tetsuro (Tokushima, JP), Tottori; Katsura (Kamita-Cho, JP), Hirose; Tsuyoshi (Tokushima, JP), Uwahodo; Yasufumi (Tokushima, JP)
Assignee: Otsuka Pharmaceutical Co., Ltd. (Tokyo, JP)
Filing Date:Jul 01, 2013
Application Number:13/932,385
Claims:1. A method of treating a patient suffering from obesity, which comprises administering to said patent a therapeutically effective amount of a carbostyril compound of formula (1), or a pharmaceutically acceptable salt or solvate thereof, wherein said patient is a mammal: ##STR00003## wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.

2. The method of claim 1 wherein the carbostyril compound is 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxyl)-3,4-dihydrocarbostyri- l.
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Teva
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Queensland Health
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US Army
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Julphar
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Cerilliant

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