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Generated: February 18, 2018

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Title:Myocardial perfusion imaging methods and compositions
Abstract: A myocardial imaging method that is accomplished by administering one or more adenosine A.sub.2A adenosine receptor agonist to a human undergoing myocardial imaging as well as pharmaceutical compositions comprising at least one A.sub.2a receptor agonist, at least one liquid carrier, and at least one co-solvent.
Inventor(s): Belardinelli; Luiz (Palo Alto, CA), Rosner; Mitchell (Mountain View, CA)
Assignee: Gilead Sciences, Inc. (Foster City, CA)
Filing Date:Mar 21, 2013
Application Number:13/848,614
Claims:1. A method for myocardial perfusion imaging comprising administering to a human subject in need thereof a compound which has the formula: ##STR00020## with saline and followed by a radionuclide, wherein the myocardium is examined for areas of insufficient blood flow following the administration of the radionuclide.

2. The method of claim 1, wherein the method comprises administering the compound by intravenous (iv) bolus.

3. A method for myocardial perfusion imaging comprising administering a single bolus intravenous injection of a pharmaceutical composition comprising a compound which has the formula: ##STR00021## to a human subject in need thereof, wherein the compound is administered in an amount of 10 .mu.g to about 1000 .mu.g, and the amount is independent of the human subject's weight.
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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Chinese Patent Office
Harvard Business School

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