.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 8,771,715

« Back to Dashboard

Details for Patent: 8,771,715

Title:Compositions and methods for treatment
Abstract: The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
Inventor(s): Oslob; Johan (Sunnyvale, CA), Shen; Wang (San Mateo, CA), Barr; Kenneth (Boston, MA), Zhong; Min (Palo Alto, CA)
Assignee: Sarcode Bioscience Inc. (Brisbane, CA)
Filing Date:Jan 21, 2011
Application Number:13/011,760
Claims:1. A pharmaceutical composition comprising an effective amount of a compound having the following formula: ##STR00033## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle, wherein the composition is in the form of liquid drops, liquid wash, gel, ointment, liposomes, solution, cream, powder, foam, crystals, spray, aerosol, or liquid suspension.

2. A pharmaceutical composition comprising an effective amount of a compound having the following formula: ##STR00034## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle, wherein the pharmaceutically acceptable vehicle is suitable for ocular administration, wherein the composition is formulated as an insert or implant, subconjunctival injection, intraocular injection, periocular injection, retrobulbar injection, or intracameral injection.

3. The pharmaceutical composition of claim 2 wherein the insert or implant comprises a selective release device comprising a formulation wherein the compound is released in a sustained fashion.

4. The pharmaceutical composition of claim 3 wherein the formulation comprises a biocompatible polymer.

5. The pharmaceutical composition of claim 2, further comprising a preservative.

6. The pharmaceutical composition of claim 1, further comprising a preservative.

7. The pharmaceutical composition of claim 1, wherein the composition is in the form of liquid drops.

8. The pharmaceutical composition of claim 1, wherein the composition is in the form of a liquid wash.

9. The pharmaceutical composition of claim 1, wherein the composition is in the form of a gel.

10. The pharmaceutical composition of claim 1, wherein the composition is in the form of an ointment.

11. The pharmaceutical composition of claim 1, wherein the composition is in the form of liposomes.

12. The pharmaceutical composition of claim 1, wherein the composition is in the form of a solution.

13. The pharmaceutical composition of claim 1, wherein the composition is in the form of a cream.

14. The pharmaceutical composition of claim 1, wherein the composition is in the form of a powder.

15. The pharmaceutical composition of claim 1, wherein the composition is in the form of a foam.

16. The pharmaceutical composition of claim 1, wherein the composition is in the form of crystals.

17. The pharmaceutical composition of claim 1, wherein the composition is in the form of a spray.

18. The pharmaceutical composition of claim 1, wherein the composition is in the form of an aerosol.

19. The pharmaceutical composition of claim 1, wherein the composition is in the form of a liquid suspension.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc