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Serving leading biopharmaceutical companies globally:

US Army
Argus Health
Daiichi Sankyo

Generated: November 23, 2017

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Title:Drive mechanisms suitable for use in drug delivery devices
Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
Inventor(s): Veasey; Robert Frederick (Warwickshire, GB), Langley; Christopher Nigel (Warwickshire, GB), Wimpenny; Steven (Warwickshire, GB)
Assignee: Sanofi-Aventis Deutschland GmbH (Frankfurt am Main, DE)
Filing Date:Sep 09, 2013
Application Number:14/021,729
Claims:1. A dose setting and delivery mechanism for a disposable pen-type injector comprising, a) an exterior housing; b) a dose dial grip releasably engaged with a drive sleeve through a clutch such that during dose setting the drive sleeve and dose dial grip are rotationally fixed; c) a non-circular cross section piston rod threadedly engaged with an interior housing fixed to the exterior housing; d) a nut having external splines that is configured to rotate relative to the piston rod during dose setting and to move axially in proportion to a set dose; e) a dose dial sleeve having an external surface with numerals indicative of a set dose that is threadedly engaged with the exterior housing; and f) a unidirectional coupling configured to prevent rotation of the piston rod during dose setting and to allow the piston rod to rotate during dose delivery.

2. The mechanism of claim 1 further comprising a stored energy drive mechanism configured to drive the drive sleeve during dose delivery.

3. The mechanism of claim 2 wherein the stored energy drive mechanism comprises a spring.

4. The mechanism of claim 1 further comprising a "T" shaped dose button configured to be depressed to deliver a set dose and to drive the drive sleeve in an axial direction.

5. The mechanism of claim 1 further characterized in that the dose dial sleeve is axially displaceable relative to the piston rod.

6. The mechanism of claim 5 further characterized in that the dose dial sleeve is not rotatable relative to the piston rod during dose delivery.

7. The mechanism of claim 1 further comprising a clicker associated with the drive sleeve and configured to cause a series of audible and tactile clicks upon dose setting.
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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Express Scripts
Cantor Fitzgerald
US Department of Justice
Queensland Health

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