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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
QuintilesIMS
Harvard Business School
US Department of Justice
UBS
Express Scripts
AstraZeneca
US Army
Deloitte

Generated: June 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,461,140

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Title:Synthetic bile acid compositions and methods
Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
Inventor(s): Moriarty; Robert M. (Michiana City, IN), David; Nathaniel E. (Los Angeles, CA), Mahmood; Nadir Ahmeduddin (Calabasas, CA)
Assignee: Kythera Biopharmaceuticals, Inc. (Calabasas, CA)
Filing Date:Jun 01, 2012
Application Number:13/486,955
Claims:1. An aqueous pharmaceutical formulation comprising about 0.1% w/v to about 2% w/v deoxycholate and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt.

2. The formulation of claim 1, wherein the deoxycholate has a .sup.14C content of less than 0.9 ppt.

3. The pharmaceutical formulation of claim 1, which is suitable for subcutaneous injection.

4. The pharmaceutical formulation of claim 1, wherein the deoxycholate has a .sup.14C content of 0.87 ppt.

5. The pharmaceutical formulation of claim 1, wherein the deoxycholate has a .sup.14C content of 0.88 ppt.

6. The pharmaceutical formulation of claim 1, wherein the deoxycholate has a .sup.14C content of 0.89 ppt.

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Cantor Fitzgerald
Federal Trade Commission
Express Scripts
Teva
Moodys
Fuji
Boehringer Ingelheim
Daiichi Sankyo

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