Details for Patent: 8,354,453
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Title: | Bupropion hydrobromide and therapeutic applications |
Abstract: | A method of reducing the incidences of bupropion induced seizures by coadministration of a bromide salt with a bupropion salt. |
Inventor(s): | Williams; Robert Parry (Enniskerry, IE), Silverstone; Peter Harris (Alberta, CA) |
Assignee: | Valeant International Bermuda (Hamilton, BM) |
Filing Date: | Nov 18, 2009 |
Application Number: | 12/620,720 |
Claims: | 1. A method of reducing the incidences of bupropion induced seizures comprising coadministration of a bromide salt with a bupropion salt, wherein the bromide salt is administered in an amount of less than about 3.5 mg/kg. 2. The method of claim 1 wherein the bromide salt is sodium bromide. 3. The method of claim 1 wherein the bupropion salt is bupropion hydrochloride. 4. The method of claim 1 wherein the bromide salt is administered in amount of from about 1.0 to about 3.5 mg/kg. 5. The method of claim 4 wherein the bromide salt is sodium bromide. 6. The method of claim 5 wherein the bupropion salt is bupropion hydrochloride. |