.

Make Better Decisions

  • Analyze global market entry opportunities
  • Uncover prior art in expired and abandoned patents
  • Obtain formulation and manufacturing information

► See Plans & Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving 500+ biopharmaceutical companies globally:

Medtronic
Cipla
Express Scripts
Julphar
Citi
McKesson
Dow
Daiichi Sankyo
US Army
Mallinckrodt

Generated: September 24, 2017

DrugPatentWatch Database Preview

Details for Patent: ► Subscribe

« Back to Dashboard

Details for Patent: ► Subscribe

Title:Prodrugs of GABA analogs, compositions and uses thereof
Abstract: The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
Inventor(s): Gallop; Mark A. (Santa Clara, CA), Cundy; Kenneth C. (Redwood City, CA), Zhou; Cindy X. (Palo Alto, CA), Yao; Fenmei (Mountain View, CA), Xiang; Jia-Ning (Palo Alto, CA), Ollman; Ian R. (San Mateo, CA), Qiu; Fayang G. (Mountain View, CA)
Assignee: XenoPort, Inc. (Santa Clara, CA)
Filing Date:Jul 01, 2010
Application Number:12/828,764
Claims:1. A compound having the formula: ##STR00063## a diastereomer thereof or a pharmaceutically acceptable salt thereof.

2. A compound having the formula: ##STR00064## a diastereomer thereof or a pharmaceutically acceptable salt thereof.

3. A compound having the formula: ##STR00065## a diastereomer thereof or a pharmaceutically acceptable salt thereof.

4. A pharmaceutical composition comprising a compound of formula: ##STR00066## or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable vehicle, wherein: R.sup.7 and R.sup.14 are each hydrogen; R.sup.13 is selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl and sec-butyl; and R.sup.25 is selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, n-pentyl, isopentyl, sec-pentyl, neopentyl, and 1,1-diethoxyethyl.

5. The pharmaceutical composition of claim 4 wherein R.sup.13 is methyl.

6. The pharmaceutical composition of claim 4, wherein R.sup.25 is methyl, ethyl, n-propyl or isopropyl.

7. The pharmaceutical composition of any one of claims 4-6 which is an oral sustained release dosage form.

8. A pharmaceutical composition comprising a compound having the formula: ##STR00067## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle.

9. An oral sustained release dosage form comprising a compound having the formula: ##STR00068## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Serving 500+ biopharmaceutical companies globally:

Colorcon
Fish and Richardson
Covington
Cantor Fitzgerald
Argus Health
Cipla
Chinese Patent Office
Queensland Health
AstraZeneca
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted Heap | Mobile and Web Analytics
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:



Google
Twitter
Google Plus
botpot