Details for Patent: 8,158,653
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Title: | Pharmaceutical compositions of 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-amino isoindoline |
Abstract: | Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines are disclosed. The compounds are useful, for example, in reducing the levels of TNF.alpha. in a mammal. |
Inventor(s): | Muller; George W. (Bridgewater, NJ), Stirling; David I. (Branchburg, NJ), Chen; Roger Shen-Chu (Edison, NJ) |
Assignee: | Celgene Corporation (Summit, NJ) |
Filing Date: | Apr 12, 2006 |
Application Number: | 11/401,862 |
Claims: | 1. An oral dosage form in the form of a capsule or a tablet comprising a therapeutically effective amount of compound of the formula: ##STR00007## or an acid addition salt thereof, and a pharmaceutically acceptable excipient. 2. The oral dosage form of claim 1, wherein the compound is present at an amount of from 1 to 100 mg. |