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Generated: October 19, 2018

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Details for Patent: 8,158,580

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Title:Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin
Abstract: Disclosed are pharmaceutical compositions containing a cyclodextrin and a therapeutically effective amount of a glycopeptide antibiotic or a salt thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering such pharmaceutical compositions.
Inventor(s): Judice; J. Kevin (El Granada, CA), Shaw; Jeng-Pyng (Saratoga, CA), Mu; YongQi (Los Altos, CA), Conner; Michael W. (Half Moon Bay, CA), Pace; John L. (San Anselmo, CA)
Assignee: Theravance, Inc. (South San Francisco, CA)
Filing Date:Apr 29, 2009
Application Number:12/431,940
Claims:1. A pharmaceutical composition comprising: (a) a lipidated vancomycin derivative, or a pharmaceutically-acceptable salt thereof; and (b) a cyclodextrin selected from hydroxypropyl-.beta.-cyclodextrin and sulfobutyl ether .beta.-cyclodextrin.

2. The pharmaceutical composition of claim 1, wherein the cyclodextrin is hydroxypropyl-.beta.-cyclodextrin.

3. The pharmaceutical composition of claim 1, wherein the cyclodextrin is sulfobutyl ether .beta.-cyclodextrin.

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