Details for Patent: 8,143,271

Title:	Compounds and methods for kinase modulation, and indications therefor
Abstract:	Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
Inventor(s):	Ibrahim; Prabha N. (Mountain View, CA), Artis; Dean R. (Kensington, CA), Bremer; Ryan (Oakland, CA), Zhang; Chao (Moraga, CA), Zhang; Jiazhong (Foster City, CA), Tsai; James (Vallejo, CA), Hirth; Klaus-Peter (San Francisco, CA), Bollag; Gideon (Orinda, CA), Cho; Hanna (Oakland, CA)
Assignee:	Plexxikon Inc. (Berkeley, CA)
Filing Date:	Aug 23, 2011
Application Number:	13/216,200
Claims:	1. A compound of the formula: ##STR03472## 2. A pharmaceutical composition comprising the compound of claim 1, and a pharmaceutically acceptable carrier, diluent or excipient. 3. The pharmaceutical composition of claim 2 in unit dosage form. 4. The pharmaceutical composition of claim 3, wherein the unit dosage form is a tablet. 5. A pharmaceutically acceptable salt of the compound of the formula: ##STR03473## 6. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 5, and a pharmaceutically acceptable carrier, diluent or excipient. 7. The pharmaceutical composition of claim 6 in unit dosage form. 8. The pharmaceutical composition of claim 7, wherein the unit dosage form is a tablet.