Details for Patent: 8,071,648
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Title: | Topical nepafenac formulations |
Abstract: | Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration. |
Inventor(s): | Wong; Warren (Fort Worth, TX) |
Assignee: | Novartis AG (Basel, CH) |
Filing Date: | Sep 23, 2010 |
Application Number: | 12/888,631 |
Claims: | 1. A topically administrable ophthalmic composition consisting of a) 0.1% (w/v) nepafenac; b) 0.5% (w/v) carbomer; c) 0.01% (w/v) tyloxapol; d) 0.4% (w/v) sodium chloride; e) 2.4% (w/v) mannitol; f) a pH-adjusting agent in an amount sufficient to cause the composition to have a pH of 7.3-7.7; g) 0.005% (w/v) benzalkonium chloride; h) 0.01% edetate disodium; and i) purified water. |