You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: March 29, 2024

Details for Patent: 7,935,731


✉ Email this page to a colleague

« Back to Dashboard


Title:Methods for concomitant administration of colchicine and macrolide antibiotics
Abstract: Methods for concomitant administration of colchicine together with one or more macrolide antibiotics, e.g., clarithromycin, are disclosed. Such methods reduce the dangers commonly associated with such concomitant administration and provide additional benefits.
Inventor(s): Davis; Matthew W. (Erwinna, PA)
Assignee: Mutual Pharmaceutical Company, Inc. (Philadelphia, PA)
Filing Date:May 25, 2010
Application Number:12/786,921
Claims:1. A method of using colchicine for the treatment of Familial Mediterranean Fever in a human patient in need of treatment thereof, said method comprising: orally administering a reduced colchicine dosage amount to the human patient in need of treatment for Familial Mediterranean Fever who is concomitantly receiving administration of clarithromycin within 1 to 2 days of oral administration of colchicine, wherein the reduced colchicine dosage amount is reduced compared to a daily dosage amount to be administered in the absence of concomitant clarithromycin and is about 0.3 mg of colchicine twice per day, wherein the daily dosage amount of colchicine in the absence of concomitant clarithromycin is: TABLE-US-00009 Daily dosage amount Age Usual Maximum Adults and children >12 years 1.2 mg 2.4 mg Children >6 to 12 years 0.9 mg 1.8 mg Children 4 to 6 years 0.3 mg 1.8 mg

and wherein the dose of clarithromycin is 250 mg twice per day.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.