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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
US Department of Justice
Argus Health
Queensland Health

Generated: May 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,786,102

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Title:Steroids as agonists for FXR
Abstract: The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Inventor(s): Pellicciari; Roberto (Perugia, IT)
Assignee: Intercept Pharmaceuticals, Inc. (New York, NY)
Filing Date:Nov 21, 2006
Application Number:11/602,307
Claims:1. A method for activating FXR in a mammal comprising administering to the mammal, in an amount effective for activating FXR, a compound: ##STR00007## or a pharmaceutically acceptable salt or amino acid conjugate thereof, wherein said mammal is in need of treatment of an FXR mediated disease, further wherein said disease is cholestatic liver disease.

2. The method according to claim 1, wherein the compound is a pharmaceutically acceptable salt of the compound.

3. The method according to claim 1, wherein the compound is the amino acid conjugate of the compound.

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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Chinese Patent Office
Fish and Richardson
US Department of Justice

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