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|Title:||Process for producing imide compound|
|Abstract:||The present invention provides an excellent industrial process for producing an imide compound hydrochloride. The process for producing an imide compound hydrochloride of the formula (2): ##STR00001## or an enantiomer thereof, which comprises treating a compound of the formula (1): ##STR00002## or an enantiomer thereof with an aqueous hydrochloric acid solution in a hydrophilic solvent, followed by crystallizing the resultant.|
|Inventor(s):||Kakiya; Yuzo (Ibaraki, JP), Oda; Mayumi (Osaka, JP)|
|Assignee:||Dainippon Sumitomo Pharma Co., Ltd. (Osaka-Shi, Osaka, JP)|
|Filing Date:||Jul 27, 2004|
|Claims:||1. A process for producing an imide compound hydrochloride of the formula (2): ##STR00008## or an enantiomer thereof, which comprises treating a compound of the formula (1): ##STR00009## or an enantiomer thereof with 1.8 to 5.0% aqueous hydrochloric acid solution in acetone, crystallizing the resultant hydrochloride of the formula (2), and isolating the crystallized hydrochloride of the formula (2). |
2. The process for producing the imide compound hydrochloride according to claim 1, wherein the aqueous hydrochloric acid solution is a 3.0-5.0% aqueous hydrochloric acid solution.
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