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|Abstract:||Disclosed herein are analogs of tetrahydrobiopterin, compositions containing the same, and methods of treating an individual suffering from a condition responsive to tetrahydrobiopterin by administration of the analog. These analogs are contemplated for use wherever tetrahydrobiopterin is currently used to treat conditions responsive to tetrahydrobiopterin therapies.|
|Inventor(s):||Kakkis; Emil D. (Novato, CA)|
|Assignee:||BioMarin Pharmaceutical Inc. (Novato, CA)|
|Filing Date:||Oct 29, 2008|
|Claims:||1. A compound having a formula ##STR00034## or a pharmaceutically acceptable salt thereof. |
2. A composition comprising a compound of claim 1 and a pharmaceutically acceptable diluent, carrier, or excipient.
3. The composition of claim 2, wherein the composition is suitable for oral administration.
4. The composition of claim 3, in the form of a solid.
5. The composition of claim 3, in the form of a liquid.