Details for Patent: 7,569,611

Title:	Modified release formulations of a bupropion salt
Abstract:	The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
Inventor(s):	Oberegger; Werner (Mississauga, CA), Maes; Paul (Toronto, CA), Saleh; Mohammad Ashty (Oakville, CA)
Assignee:	Biovail Laboratories International SRL. (St. Michael, BB)
Filing Date:	Jun 14, 2007
Application Number:	11/762,820
Claims:	1. A composition comprising bupropion hydrobromide and at least one other drug other than bupropion hydrobromide selected from the group consisting of anti-depressants, anti-anxiety agents, steroidal inflammatories, non-steroidal inflammatories, SSRIs, anti-migraine agents, anti-emetics, drugs for treating abuse, appetite modulators, anti-virals, vasodilators, anti-pain agents, and combinations thereof. 2. A composition according to claim 1 comprising bupropion hydrobromide and at least one other drug other than bupropion hydrobromide selected from the group consisting of a monoamine oxidase (MAO) inhibitor, a tricyclic antidepressant, a serotonin reuptake inhibitor, a selective norepinepbrine reuptake inhibitor (SNRIs), aminoketones, serotonin antagonists, dopamine reuptake inhibitors, dual reuptake inhibitors, norepinephrine enhancers, serotonin activity enhancers, dopamine activity enhancers, and combinations thereof. 3. A composition according to claim 1 comprising bupropion hydrobromide and at least one other drug other than bupropion hydrobromide selected from the group consisting of citalopram, escitalopram, venlafaxine, clozapine, melperone, amperozide, iloperidone, risperidone, quetiapene, olanzapine, ziprasidone, aripiprazole, reboxetine, VIAGRA.RTM., sertraline, paroxetine, fluoxetine, gabapentin, valproic acid, amitriptyline, lofepramine, fluvoxamine, imipramine, mirtazapine, nefazodone, nortriptyline, SAM-E and combinations thereof. 4. A composition according to claim 3, comprising bupropion hydrobromide and citalopram. 5. A composition according to claim 3, comprising bupropion hydrobromide and escitalopram. 6. A composition according to claim 3, comprising bupropion hydrobromide and venlafaxine. 7. A composition according to claim 3, comprising bupropion hydrobromide and quetiapene. 8. A composition according to claim 1, wherein the bupropion hydrobromide has greater stability measured by less degradation products compared to bupropion hydrochloride.