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Details for Patent: 7,553,872

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Details for Patent: 7,553,872

Title:Compounds and compositions for delivering active agents
Abstract: Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
Inventor(s): Sarubbi; Donald J. (Hartsdale, NY), Barantsevitch; Evgueni (Scarsdale, NY)
Assignee: Emisphere Technologies, Inc. (Tarrytown, NY)
Filing Date:Feb 13, 2006
Application Number:11/354,045
Claims:1. A composition comprising: (A) at least one active agent selected from human growth hormone, interferon, heparin, low molecular weight heparin, parathyroid hormone, and combinations thereof; and (B) the compound represented by the formula ##STR00022## or a salt thereof.

2. The composition of claim 1 wherein said active agent is human growth hormone.

3. The composition of claim 1 wherein said active agent is interferon.

4. The composition of claim 1 wherein said active agent is heparin.

5. The composition of claim 1 wherein said active agent is low molecular weight heparin.

6. The composition of claim 1 wherein said active agent is parathyroid hormone.

7. A dosage unit form comprising (A) a composition as defined in claim 1 and (B) (a) an excipient, (b) a diluent, (c) a disintegrant, (d) a lubricant, (e) a plasticizer, (f) a colorant, (g) a dosing vehicle, or (h) any combination thereof.

8. The dosage unit form of claim 7 comprising a tablet, a capsule, or a liquid.

9. The dosage unit form of claim 7 wherein said dosing vehicle is selected from the group consisting of water, 1,2-propane diol, ethanol, or any combination thereof.

10. The dosage unit form of claim 7 wherein said active agent is human growth hormone.

11. The dosage unit form of claim 7 wherein said active agent is interferon.

12. The dosage unit form of claim 7 wherein said active agent is heparin.

13. The dosage unit form of claim 7, wherein said active agent is low molecular weight heparin.

14. The dosage unit form of claim 7 wherein said active agent is parathyroid hormone.

15. A method for administering an active agent to an animal in need of said agent, said method comprising administering orally to said animal the composition of claim 1.

16. The method of claim 15 wherein said active agent is human growth hormone.

17. The method of claim 15 wherein said active agent is interferon.

18. The method of claim 15 wherein said active agent is heparin.

19. The method of claim 15 wherein said active agent is low molecular weight heparin.

20. The method of claim 15 wherein said active agent is parathyroid hormone.
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