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Details for Patent: 7,553,299

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Details for Patent: 7,553,299

Title:Drive mechanisms suitable for use in drug delivery devices
Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a piston rod, and a unidirectional coupling between the housing and the piston rod. The drive mechanism may also include a dose dial sleeve and a drive sleeve, with a clutch mean located therebetween to prevent relative rotation between the dial sleeve and the drive sleeve when in a coupled state and to permit relative rotation between the dial sleeve and the drive sleeve when in a de-coupled state.
Inventor(s): Veasey; Robert Frederick (Leamington Spa, GB), Langley; Christopher Nigel (Leamington Spa, GB), Wimpenny; Steven (Leamington Spa, GB)
Assignee: DCA Design International Ltd. (Warwick, GB)
Filing Date:Mar 02, 2004
Application Number:10/790,024
Claims:1. A drive mechanism for use in a drug delivery device comprising: a housing having an internal and an external thread; a piston rod having a non-circular cross section, and which is threadedly engaged with the internal thread of the housing; a unidirectional coupling located between the housing and the piston rod; a dose dial sleeve, which is threadedly engaged with the external thread of the housing and being rotatable with respect to the housing; a drive sleeve, located between the housing and the piston rod, which is axially displaceable but not rotatable with respect to the piston rod; and a clutch means located between the drive sleeve and the dose dial sleeve, which a) when the dose dial sleeve and the drive sleeve are de-coupled by the clutch means, rotation of said dose dial sleeve with respect to the drive sleeve is allowed; and b) when the dose dial sleeve and the drive sleeve are coupled by the clutch means, rotation of the dose dial sleeve with respect to the said drive sleeve is prevented.

2. An assembly for use in a drug delivery device comprising the drive mechanism of claim 1.

3. A drug delivery device comprising the drive mechanism of claim 1.

4. The drug delivery device according to claim 3, wherein the delivery device is a pen-type device.

5. The drug delivery device according to claim 3, wherein the delivery device is an injector-type device.

6. The drug delivery device according to claim 3, wherein the device further comprises a needle.

7. The drug delivery device according to claim 3, wherein the device is a needle-free device.

8. A method of delivering a drug, comprising: providing the device of claim 3, dispensing a medicinal product with the device.

9. The method of manufacturing or assembling a drug delivery device, comprising the step of providing a drive mechanism according to claim 1.

10. A drug delivery device comprising the assembly of claim 2.

11. The drug delivery device of claim 10, wherein the device is a pen-type device.

12. The drug delivery device of claim 10, wherein the device is an injector-type device.

13. The drug delivery device of claim 10, further comprising a needle.

14. The drug delivery device of claim 10, wherein the device is a needle-free device.

15. A method of delivering a drug, comprising: providing the device of claim 10, dispensing a medicinal product with the device.

16. The method of claim 15, wherein dispensing a medicinal product includes dispensing a pharmaceutical formulation from the device, wherein the pharmaceutical formulation comprises an active compound selected from the group consisting of insulin, growth hormone, low molecular weight heparin, analogues thereof, and derivatives thereof.

17. A method of manufacturing or assembling a drug delivery device, comprising providing the assembly of claim 2.

18. The method of claim 8, wherein dispensing a medicinal product includes dispensing a pharmaceutical formulation comprising an active compound selected from the group consisting of insulin, growth hormone, low molecular weight heparin, analogues thereof, and derivatives thereof.
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