Details for Patent: 7,449,469
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Title: | Prostaglandin derivatives |
Abstract: | Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. |
Inventor(s): | Ongini; Ennio (Milan, IT), Chiroli; Valerio (Milan, IT), Benedini; Francesca (Milan, IT), Del Soldato; Piero (Italy, IT) |
Assignee: | Nicox S.A. (FR) |
Filing Date: | Aug 20, 2007 |
Application Number: | 11/841,628 |
Claims: | 1. A pharmaceutical composition comprising a mixture of a compound according to the following formula ##STR00047## and: (i) a beta-blocker or a nitrooxy derivative thereof; or (ii) a carbonic anhydrase inhibitor or a nitrooxy derivative thereof; or (iii) an adrenergic agonist or a nitrooxy derivative thereof. 2. A pharmaceutical composition comprising a mixture of a compound according to the following formula ##STR00048## and timolol or a nitrooxy derivative thereof. |