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Serving 500+ biopharmaceutical companies globally:

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Generated: August 17, 2017

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Title:Sulfamides and their use as endothelin receptor antagonists
Abstract: The invention relates to novel sulfamides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
Inventor(s): Bolli; Martin (Allschwil, CH), Boss; Christoph (Allschwil, CH), Fischli; Walter (Allschwil, CH), Clozel; Martine (Saint-Louis, FR), Weller; Thomas (Binningen, CH)
Assignee: Actelion Pharmaceuticals Ltd. (Allschwil, CH)
Filing Date:Apr 07, 2006
Application Number:11/400,697
Claims:1. A compound selected from the group consisting of the compounds having the following structures: ##STR00535## ##STR00536## ##STR00537## ##STR00538## ##STR00539## ##STR00540## ##STR00541## ##STR00542## or a salt of such a compound.

2. The compound of claim 1, which has the following structure ##STR00543## or a salt of this compound.

3. The compound of claim 1, which has the following structure ##STR00544## or a salt of this compound.

4. The compound of claim 1, which has the following structure ##STR00545## or a salt of this compound.

5. The compound of claim 1, which has the following structure ##STR00546## or a salt of this compound.
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Serving 500+ biopharmaceutical companies globally:

Accenture
Baxter
Farmers Insurance
Fish and Richardson
Queensland Health
McKinsey
Merck
Healthtrust
Colorcon
Mallinckrodt

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