.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 7,244,412

« Back to Dashboard

Details for Patent: 7,244,412

Title:Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia
Abstract: Disclosed is a method of manipulating the rate of upper gastrointestinal transit of a substance in a mammal. Also disclosed are methods of manipulating satiety and post-prandial visceral blood flow. A method of treating visceral pain or visceral hypersensitivity in a human subject is also described. A method for prolonging the residence time of an orally or enterally administered substance by promoting its dissolution, bioavailability and/or absorption in the small intestine is also described. These methods are related to a method of transmitting to and replicating at a second location in the central nervous system a serotonergic neural signal originating at a first location in the proximal or distal gut of a mammal and/or a method of transmitting to and replicating at a second location in the upper gastrointestinal tract a serotonergic neural signal originating at a first location in the proximal or distal gut.
Inventor(s): Lin; Henry C. (Manhattan Beach, CA)
Assignee: Cedars-Sinai Medical Center (Los Angeles, CA)
Filing Date:May 26, 2004
Application Number:10/853,824
Claims:1. A method for treating obesity in a mammalian subject comprising administering peptide YY to said mammal.

2. The method of claim 1 wherein said subject is a human.

3. The method of claim 1 wherein said peptide YY is administered at a dose of about 0.8 micrograms (.mu.g)/kg weight of said mammal/hour (hr).

4. The method of claim 3 wherein said peptide YY is administered by an oral or enteral delivery route.

5. The method of claim 3 wherein said peptide YY is administered by an oral delivery route.

6. A method of claim 1 wherein said peptide YY is administered parenterally.

7. The method of claim 6 wherein said peptide YY is administered at about 0.8 micrograms (.mu.g)/kg weight of the mammal/hour(hr).

8. A method for treating obesity in a human subject comprising parenterally administering to said human peptide, peptide YY at a dose of about 0.8 micrograms (.mu.g)/kg weight of the subject.

9. A method of inducing satiety in a mammalian subject comprising administering peptide YY to said mammalian subject.

10. The method of claim 9 wherein said peptide YY is administered at a dose of about 0.8 micrograms (.mu.g)/kg weight of the subject.

11. The method of claim 10 wherein the peptide YY is administered by an oral or enteral route.

12. The method of claim 9 wherein said subject is a human.

13. The method of claim 9 wherein the peptide YY is administered parenterally.

14. The method of claim 13 wherein said peptide YY is administered at about 0.8 .mu.g/kg weight of the subject/hr.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc